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Physical Activity After Breast Cancer Surgery: Does Depression Make Exercise Feel More Effortful than It Actually Is?

  • Avelina C. PadinEmail author
  • Stephanie J. Wilson
  • Brittney E. Bailey
  • William B. Malarkey
  • Maryam B. Lustberg
  • William B. Farrar
  • Stephen P. Povoski
  • Doreen M. Agnese
  • Raquel E. Reinbolt
  • Robert Wesolowski
  • Nicole Williams
  • Sagar Sardesai
  • Bhuvaneswari Ramaswamy
  • Anne M. Noonan
  • Jeffrey B. Vandeusen
  • Garrie J. Haas
  • Janice K. Kiecolt-Glaser
Article

Abstract

Background

Prior to treatment, breast cancer patients are less physically fit compared to peers; during cancer treatment, their fitness typically declines. Depressive symptoms are associated with reduced activity up to 5 years post-treatment, but research has not identified mechanisms linking depression and lower activity. The current study assessed relationships among breast cancer patients’ depression and perceived exertion during exercise as well as heart rate, an objective indicator of exertion.

Methods

Participants were 106 breast cancer patients, stages I–IIIA, who completed surgery but had not started adjuvant treatment. Heart rate and self-rated exertion, measured using the Borg Scale of Perceived Exertion, were assessed every 2 min during a graded exercise test. Depression was assessed using the CES-D and a structured clinical interview.

Results

Compared to women below the CES-D clinical cutoff, women with significant depressive symptoms reported steeper increases in exertion during the exercise test (p = .010) but had similar heart rates (p = .224) compared to women below the cutoff. Major depression history was unrelated to perceived exertion (ps > .224) and heart rate (ps > .200) during exercise.

Conclusions

Women with currently elevated depressive symptoms experienced exercise as more difficult compared to women below the CES-D cutoff, but these self-perceptions did not reflect actual heart rate differences. Depression may make exercise feel more demanding, which could ultimately decrease patients’ likelihood of engaging in regular exercise. Results support the use of depression screening tools following breast cancer surgery to identify and intervene on individuals at risk for decreased physical activity during survivorship.

Keywords

Breast cancer Physical activity Exercise Perceived exertion Depression Depressive symptoms 

Notes

Funding

This work was supported in part by the National Institutes of Health grant nos. R01 CA186720, UL1TR001070, K05 CA172296, T32 DE014320, and a Pelotonia Postdoctoral Fellowship from Ohio State University’s Comprehensive Cancer Center. The first author also receives support from the National Institutes of Health grant no. R01 CA186720-02S2, and the third author receives support from the National Institutes of Health grant no. R01 CA186720-02S1.

Compliance with Ethical Standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Conflict of Interest

The authors declare that they have no conflict of interest.

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Copyright information

© International Society of Behavioral Medicine 2019

Authors and Affiliations

  • Avelina C. Padin
    • 1
    • 2
    Email author
  • Stephanie J. Wilson
    • 1
  • Brittney E. Bailey
    • 3
  • William B. Malarkey
    • 1
  • Maryam B. Lustberg
    • 4
  • William B. Farrar
    • 5
  • Stephen P. Povoski
    • 5
  • Doreen M. Agnese
    • 5
  • Raquel E. Reinbolt
    • 4
  • Robert Wesolowski
    • 4
  • Nicole Williams
    • 4
  • Sagar Sardesai
    • 4
  • Bhuvaneswari Ramaswamy
    • 4
  • Anne M. Noonan
    • 4
  • Jeffrey B. Vandeusen
    • 4
  • Garrie J. Haas
    • 4
  • Janice K. Kiecolt-Glaser
    • 1
    • 6
  1. 1.Institute for Behavioral Medicine ResearchThe Ohio State University College of MedicineColumbusUSA
  2. 2.Department of PsychologyThe Ohio State UniversityColumbusUSA
  3. 3.Department of Mathematics and StatisticsAmherst CollegeAmherstUSA
  4. 4.Department of Internal MedicineThe Ohio State University College of MedicineColumbusUSA
  5. 5.Department of SurgeryThe Ohio State University College of MedicineColumbusUSA
  6. 6.Department of Psychiatry and Behavioral HealthThe Ohio State University College of MedicineColumbusUSA

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