Say no to drugs: wait and watch strategy for medications used in the neonatal intensive care unit (NICU)
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From the presentation of gray baby syndrome with chloramphenicol use to gasping baby syndrome with exposure from benzyl alcohol in bacteriostatic flushes, historical clinical precedence has shown that babies cared for in the neonatal intensive care unit (NICU) are at higher risk of adverse effects from medication administration than other populations [1, 2]. Historical precedence led to a discussion amongst the multi-disciplinary team questioning whether medications are used excessively in the NICU. A recent review paper by Hsieh et al.  has elaborated on this question in detail, in which a downward trend in the use of certain medications was shown.
The NICU is a very high-risk environment with a higher than normal potential for medication errors to occur. This increased potential for medication errors forms a basis for the importance of instituting safe medication practices in the NICU . Therefore, a vigilant strategy is needed regarding the non-beneficial use of medications in...
HT contributed to design, acquisition and analysis/interpretation of data, and drafting of the article. SM contributed to concept, design, acquisition and analysis/interpretation of data, and drafting of the article. NW contributed to concept, acquisition and analysis/interpretation of data and drafting of the article. KT contributed to analysis/interpretation of data. All the authors revised the article critically and approved the final version to be published.
No financial or non-financial benefits have been received or will be received from any party related directly or indirectly to the subject of this article.
Compliance with ethical standards
This article does not contain any studies with human participants or animals performed by any of the authors.
Conflict of interest
The author(s) declare no conflicts or financial interest in any product or service mentioned in the manuscript, including grants, equipment, medications, employment, gifts, and honoraria.
- 1.Wax PM. Toxicologic misfortunes and catastrophes in history. In: Nelson LS, Howland MA, Lewin NA, Smith SW, Goldrank LR, Hoffman RS, editors. Goldfrank’s toxicologic emergencies [Internet]. 11th ed. China: McGraw-Hill; 2019.Google Scholar