World Journal of Pediatrics

, Volume 8, Issue 2, pp 164–168 | Cite as

Skin prick testing in atopic eczema: atopic to what and at what age?

  • Kam-lun Ellis Hon
  • Shuxin Susan Wang
  • Wing Lam Wong
  • Wing Kwan Poon
  • Ka Yi Mak
  • Ting Fan Leung
Original Article



Atopic eczema is a common and distressing disease. This study aimed to review the age-dependent pattern of atopic sensitization to food and aeroallergens in patients with eczema by skin prick testing.


The results of skin prick test (SPT), serum IgE, bronchial challenge test, and family history of atopy in eczema patients seen at a pediatric dermatology clinic were reviewed.


SPT results were available in 816 eczema patients. In these patients, 90% had atopic sensitization to at least one aeroallergen, 69% to at least one food allergen, and 94% to at least one allergen by SPT. Together with a family history of atopy in parents or siblings and a personal history of airway atopies, 97% and 99.8% of the patients were atopic, respectively. Bronchial hyper-reactivity (BHR) was demonstrated in 44% of 339 patients. Aeroallergen was more prevalent than food allergen sensitization among children older than 10 years. The mites (D. pteronysissnus, D. farinae and Blomia Tropicalis) were the most prevalent allergens regardless of age and BHR, but D. pteronysissnus and D. farinae sensitization were more prevalent among BHRpositive patients. Beef is the least sensitized food protein in all ages.


The majority of patients with eczema are atopic to aeroallergens. The mites (D. pteronysissnus, D. farinae and Blomia Tropicalis) are the most prevalent allergens regardless of age and BHR.

Key words

aeroallergens atopic dermatitis eczema food allergens IgE skin prick test 


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Copyright information

© Children's Hospital, Zhejiang University School of Medicine and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Kam-lun Ellis Hon
    • 1
    • 2
  • Shuxin Susan Wang
    • 1
  • Wing Lam Wong
    • 1
  • Wing Kwan Poon
    • 1
  • Ka Yi Mak
    • 1
  • Ting Fan Leung
    • 1
  1. 1.Department of PediatricsThe Chinese University of Hong Kong, Prince of Wales HospitalHong KongChina
  2. 2.Department of PediatricsThe Chinese University of Hong KongHong KongChina

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