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World Journal of Pediatrics

, Volume 9, Issue 2, pp 182–184 | Cite as

Blount disease in a case of Prader-Willi syndrome: why is it not as prevalent as in obesity without Prader-Willi syndrome?

  • Susan Dulka
  • Arabinda Kumar Choudhary
  • Sosamma Methratta
  • Kristine Fortuna
Case report

Abstract

Background

Prader-Willi syndrome (PWS) is a genetic disorder causing multisystem abnormalities with obesity. Obesity is a well established cause of Blount disease.

Methods

A 7-year-old girl with PWS presented with genu varum of the left knee with deformity of the proximal medial tibial condyle, which was consistent with Blount disease.

Results

A lateral physeal stapling and subsequent osteotomy for the left proximal tibia and fibula were performed with improved anatomical alignment.

Conclusion

Blount disease has not been reported in the literature in association with PWS despite excessive obesity.

Key words

Blount disease genetics obesity Prader-Willi syndrome radiology 

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References

  1. 1.
    Jones KL. Prader-willi syndrome. In: Jones KL, eds. Smith’s recognizable patterns of human malformation, 5th ed. Philadelphia: WB Saunders Company, 1997:202–205.Google Scholar
  2. 2.
    Scott AC, Kelly CH, Sullivan E. Body mass index as a prognostic factor in development of infantile Blount disease. J Pediatr Orthop 2007;27:921–925.PubMedCrossRefGoogle Scholar
  3. 3.
    Sabharwal S, Zhao C, McClemens E. Correlation of body mass index and radiographic deformities in children with Blount disease. J Bone Joint Surg Am 2007;89:1275–1283.PubMedCrossRefGoogle Scholar
  4. 4.
    West LA, Ballock RT. High incidence of hip dysplasia but not slipped capital femoral epiphysis in patients with Prader-Willi syndrome. J Pediatr Orthop 2004;24:565–567.PubMedCrossRefGoogle Scholar
  5. 5.
    Kroonen LT, Herman M, Pizzutillo PD, Macewen GD. Prader-Willi syndrome: clinical concerns for the orthopaedic surgeon. J Pediatr Orthop 2006;26:673–679.PubMedCrossRefGoogle Scholar
  6. 6.
    Vismara L, Romei M, Galli M, Montesano A, Baccalaro G, Crivellini M, et al. Clinical implications of gait analysis in the rehabilitation of adult patients with “Prader-Willi” syndrome: a cross-sectional comparative study (“Prader-Willi” syndrome vs matched obese patients and healthy subjects). J Neuroeng Rehabil 2007;4:14.PubMedCrossRefGoogle Scholar
  7. 7.
    Theodoro MF, Talebizadeh Z, Butler MG. Body composition and fatness patterns in Prader-Willi syndrome: comparison with simple obesity. Obesity (Silver Spring) 2006;14:1685–1690.CrossRefGoogle Scholar

Copyright information

© Children's Hospital, Zhejiang University School of Medicine and Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Susan Dulka
    • 1
  • Arabinda Kumar Choudhary
    • 1
  • Sosamma Methratta
    • 1
  • Kristine Fortuna
    • 2
  1. 1.Department of RadiologyPenn State/Milton S. Hershey Medical CenterHersheyUSA
  2. 2.Department of OrthopedicsPenn State/Milton S. Hershey Medical CenterHersheyUSA

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