Blount disease in a case of Prader-Willi syndrome: why is it not as prevalent as in obesity without Prader-Willi syndrome?
Prader-Willi syndrome (PWS) is a genetic disorder causing multisystem abnormalities with obesity. Obesity is a well established cause of Blount disease.
A 7-year-old girl with PWS presented with genu varum of the left knee with deformity of the proximal medial tibial condyle, which was consistent with Blount disease.
A lateral physeal stapling and subsequent osteotomy for the left proximal tibia and fibula were performed with improved anatomical alignment.
Blount disease has not been reported in the literature in association with PWS despite excessive obesity.
Key wordsBlount disease genetics obesity Prader-Willi syndrome radiology
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- 1.Jones KL. Prader-willi syndrome. In: Jones KL, eds. Smith’s recognizable patterns of human malformation, 5th ed. Philadelphia: WB Saunders Company, 1997:202–205.Google Scholar
- 6.Vismara L, Romei M, Galli M, Montesano A, Baccalaro G, Crivellini M, et al. Clinical implications of gait analysis in the rehabilitation of adult patients with “Prader-Willi” syndrome: a cross-sectional comparative study (“Prader-Willi” syndrome vs matched obese patients and healthy subjects). J Neuroeng Rehabil 2007;4:14.PubMedCrossRefGoogle Scholar