9. Effects of Sensor Augmented Pump Use on HbA1c and C-Peptide in the First Year of Type 1 Diabetes (355-OR)
- 88 Downloads
Intensive control after onset of type 1 diabetes (T1D) has been suggested to preserve C-peptide production. Subjects with T1D used a sensor-augmented pump (SAP), after 3 days of in hospital hybrid closed loop or usual care. In the primary intent to treat analysis (Buckingham, Diabetes Care, 2013) there were no significant differences in HbA1c or in C-peptide between the two groups at 1 year. In this post-hoc analysis, we hypothesized that more frequent CGM use would be associated with lower HbA1c and preservation of C-peptide production in the SAP group. Subjects in the SAP group (n = 48) were stratified by median CGM use. HbA1c and C-peptide were compared at baseline 3, 6, 9 and 12 months.