Recent Advances in the Field of Optical Coherence Tomography

Intravascular Imaging (IK Jang, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Intravascular Imaging

Abstract

Purpose of Review

The scope of this text is to critically review the most important recent advances in the field of optical coherence tomography, both from a clinical, scientific, and technical point of view.

Recent Findings

In recent years, important steps forward have been put in the field of optimization of PCI (with a focus on optimal sizing of stents and optimization of stent expansion after implantation) and the differentiation and its possible applications of various underlying morphologic characteristics of acute coronary syndrome lesions. Several efforts have been made to elucidate underlying mechanical causes of stent thrombosis, based on optical coherence tomography (OCT) imaging. This had led to the recognition of neoatherosclerosis as an important cause for very late stent thrombosis, fueling new research into this area and to the development of intracoronary devices which could be even more safe for patients on the very long term.

Summary

With an ever increasing use for clinical and scientific applications in coronary artery disease, OCT has come to a mature and solid tool in the armamentarium of the coronary artery disease specialist. With new areas deserving more intensified focus and several innovations ahead, it seems that OCT is there to defend its position as the standard intracoronary imaging modality for the next decennium.

Keywords

Optical coherence tomography Acute coronary syndrome Stent thrombosis In-stent restenosis DAPT Bioresorbable vascular scaffold Plaque erosion Thin-cap fibroatheroma 

Abbreviations

BMS

Bare metal stent

BVS

Bioresorbable vascular scaffold

ACS

Acute coronary syndrome

DAPT

Dual antiplatelet therapy

DES

Drug-eluting stent

EEL

External elastic lamina

ISR

In-stent restenosis

IVUS

Intra-vascular ultra sound

LDL

Low-density lipoprotein

MACE

Major adverse cardiovascular events

OCT

Optical coherence tomography

PCI

Percutaneous coronary intervention

PCSK-9

Proprotein convertase subtilisin/kexin type 9

ST

Stent thrombosis

STEMI

ST segment elevation myocardial infarction

TCFA

Thin-cap fibro atheroma

VLST

Very late stent thrombosis

Notes

Compliance with Ethical Standards

Conflict of Interest

Giovanni J. Ughi declares that he has no conflict of interest.

Tom Adriaenssens reports consultancy fees from Abbott SJ Medical.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Department of Cardiovascular Sciences, Catholic University Leuven and Department of Cardiovascular MedicineUniversity HospitalsLeuvenBelgium

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