Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension

  • Andrew J. Swift
  • Laura C. Saunders
  • Tom Sproson
  • Nehal Hussain
  • Guilhem J. Collier
  • Helen Marshall
  • David G. Kiely
  • Jim M. Wild
Cardiac Magnetic Resonance (E Nagel and V Puntmann, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Cardiac Magnetic Resonance


Quantitative magnetic resonance imaging provides a comprehensive and non-invasive assessment of the heart and lungs in patients with suspected pulmonary hypertension with the potential for accurate assessment of disease severity and response to treatment. Magnetic resonance imaging (MRI) can provide detailed reliable information of heart structure and function as the heart responds to elevated right ventricle afterload in patients with progressive pulmonary vascular disease; notably, progressive changes in right ventricle volume and function are of prognostic value independent of established biomarkers. This article reviews the current literature on MRI in pulmonary hypertension and also describes new and exciting developments in imaging of the heart, pulmonary vasculature and lungs, including assessment of myocardial changes with late gadolinium-enhanced imaging and T1 mapping, evaluating changes in the proximal pulmonary vasculature using image-based computational modelling and quantitative assessment of the capillary bed using MRI perfusion analysis.


MRI Pulmonary hypertension Magnetic resonance imaging Right ventricle Diagnosis Prognosis 


Compliance with Ethical Standards

Conflict of Interest

Andrew J. Swift, Laura C. Saunders, Tom Sproson, Guilhem J. Collier, Helen Marshall and Jim M. Wild declare that they have no conflict of interest.

Nehal Hussain reports grants from Actelion.

David G. Kiely reports grants and personal fees from Actelion, grants and personal fees from Bayer, and personal fees from GSK.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Andrew J. Swift
    • 1
    • 3
  • Laura C. Saunders
    • 1
  • Tom Sproson
    • 1
  • Nehal Hussain
    • 2
  • Guilhem J. Collier
    • 1
  • Helen Marshall
    • 1
  • David G. Kiely
    • 2
    • 3
  • Jim M. Wild
    • 1
    • 3
  1. 1.Academic Unit of RadiologyUniversity of SheffieldSheffieldUK
  2. 2.Sheffield Pulmonary Vascular Disease UnitSheffieldUK
  3. 3.Institute for In Silico MedicineUniversity of SheffieldSheffieldUK

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