Current Cardiovascular Imaging Reports

, Volume 5, Issue 1, pp 45–52 | Cite as

Molecular Imaging of Macrophages in Atherosclerosis

  • Elena Aikawa
  • Sophie E. P. New
  • Tetsuro Miyazaki
  • Daiju Fukuda
  • Masanori Aikawa
Cardiac Molecular Imaging (F Jaffer, Section Editor)
  • 141 Downloads

Abstract

Macrophages contribute to the initiation, progression, and acute complications of atherosclerosis. Imaging of macrophages during disease progression provides new insights into the mechanisms of atherosclerosis. Advanced imaging techniques may serve as sensitive diagnostic tools for early detection of the disease to identify individuals with subclinical plaques and to prevent devastating complications. Furthermore, molecular imaging may monitor the effects of therapeutic interventions. Development of fully integrated molecular imaging requires dynamic multidisciplinary collaboration.

Keywords

Macrophages Atherosclerosis Imaging Inflammation Calcification Cardiac molecular imaging 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Elena Aikawa
    • 1
  • Sophie E. P. New
    • 1
  • Tetsuro Miyazaki
    • 1
  • Daiju Fukuda
    • 1
  • Masanori Aikawa
    • 1
    • 2
  1. 1.Cardiovascular Division, Department of MedicineBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA
  2. 2.Center for Excellence in Vascular BiologyBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA

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