Impacts of Anthropogenic Activities on Groundwater Quality in a Detritic Aquifer in SE Spain

  • Juan Antonio Luque-EspinarEmail author
  • Mario Chica-Olmo
Original Paper


The quality of both surface waters (SW) and groundwater (GW) can be affected by anthropogenic activities and by faecal pollution sources from humans and animals. This study investigated the concentration of a group of chemical markers for tracking anthropogenic pollution in the Vega de Granada aquifer (VGA). A group of contaminants of emerging concern (CECs) such as amoxicillin, ciprofloxacin, ibuprofen, paracetamol, pantoprazole and caffeine, trace elements (TEs) and other potential marker species of anthropogenic pollution were selected. The parameter values (PV) for these contaminants in many of the samples exceeded it the guideline values. We also analysed some vegetables (VEG) grown in the area. The most alarming finding was that amoxicillin, paracetamol, ibuprofen and caffeine were detected in all the samples. Geostatistical methods were used to map the spatial distribution of the estimated PC scores for each principal component extracted (PCi). All the markers selected, including the CECs, appeared in different sectors of the aquifer. By analysing the results for the different parameters, it was possible to clearly define the areas affected by anthropic activities (urban and agricultural) and distinguish them from other areas with a water quality that is almost natural and is less influenced by human activity. This is a first attempt to map a group of CECs and TECs that can be hazardous to human health and the environment.


Anthropic activities Cecs Geostatistics Water resources Sewage Toxicity risk 



This research has been supported by Research Group RNM-122 of the Junta de Andalucía (Spain) and by the Geological Survey of Spain (IGME) via the SOILWATER project.

Supplementary material

12403_2019_327_MOESM1_ESM.doc (78 kb)
Supplementary file1 (DOC 78 kb)
12403_2019_327_MOESM2_ESM.doc (33 kb)
Supplementary file2 (DOC 33 kb)


  1. Avila-Pérez P, Balcazar M, Zarazúa-Ortega G, Barcelo Quinta I, Díaz-Delgado C (1999) Heavy metal concentrations in water and bottom sediments of a Mexican reservoir. Sci Total Environ 234:185–196CrossRefGoogle Scholar
  2. Balakrishna K, Rath A, Praveenkumarreddy Y, Guruge KS, Subedi B (2017) A review of the occurrence of pharmaceuticals and personal cue products in Indian water bodies. Ecotoxicol Environ Saf 137:113–120CrossRefGoogle Scholar
  3. Boente C, Matanzas N, García-González N, Rodríguez-Valdés E, Gallego JR (2017) Trace elements of concern affecting urban agriculture in industrialized areas: a multivariate approach. Chemos 183:546–556CrossRefGoogle Scholar
  4. Buerge I, Poiger T, Muller M, Buser H (2003) Caffeine, an anthropogenic marker for wastewater contamination of surface waters. Environ Sci Technol 27:691–700CrossRefGoogle Scholar
  5. Caliman FA, Gavrilescu M (2009) Pharmaceutical, personal care products and endocrine disrupting agents in the environment—review. Clean Soil Air Water 37:277–303CrossRefGoogle Scholar
  6. Camacho LM, Gutiérrez M, Alarcón-Herrera MT, Villalba M, Deng S (2011) Occurrence and treatment of arsenic in groundwater and soil in northern Mexico and southwestern USA. Chemosphere 83:211–225CrossRefGoogle Scholar
  7. Chica-Olmo M, Luque-Espinar JA, Rodriguez-Galiano V, Pardo-Igúzquiza E, Chica-Rivas L (2014) Categorical indicator kriging for assessing the risk of groundwater nitrate pollution: the case of Vega de Granada aquifer (SE Spain). Sci Total Environ 470–471:229–239CrossRefGoogle Scholar
  8. Chica-Olmo M, Peluso F, Luque-Espinar JA, Rodríguez-Galiano V, Pardo-Igúzquiza E (2017) A methodology for assessing public health risk associated with groundwater nitrate contamination: a case study in an agricultural setting (southern Spain). Environ Geoch Health 39:1117–1132CrossRefGoogle Scholar
  9. Chilès JP, Delfiner P (1999) Geostatistics: modeling spatial uncertainty. Wiley, Toronto, p 720CrossRefGoogle Scholar
  10. CLC (2012) CORINE Land Cover. Copyright Copernicus Programme, European Environment AgencyGoogle Scholar
  11. Confederación Hidrográfica del Guadalquivir CHG (2015) Plan Hidrológico de la demarcación hidrográfica del Guadalquivir (2015–2021). Anejo n° 3–Descripción de usos, demandas y presiones. p 373Google Scholar
  12. EC (1998) Council Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption. p 23Google Scholar
  13. Elizalde-Velázquez A, Gómez-Oliván LM, Galar-Martínez M, Islas-Flores H, Dublán-García O, San Juan-Reyes N (2016) Amoxicillin in the aquatic environment, its fate and environmental risk. In: Larramendy ML, Soloneski S (eds) Environmental health risk—hazardous factors to living species. IntechOpen, London, pp 247–267. CrossRefGoogle Scholar
  14. Fick J, Söderstrom H, Linderg RH, Phan C, Tysklind M, Larsson DFJ (2009) Contamination of surface, ground, and drinking water from pharmaceutical production. Environ Toxicol Chem 28:2522–2527CrossRefGoogle Scholar
  15. Förstner U, Wittmann GTW (1979) Metal pollution in the aquatic environment. Springer, Berlin. CrossRefGoogle Scholar
  16. Frisbie SH, Mitchell EJ, Mastera LJ, Maynard DM, Yusuf AZ, Siddiq MY, Ortega R, Dunn RK, Westerman DS, Bacquart T, Sarkar B (2009) Public health strategies for western Bangladesh that address arsenic, manganese, uranium, and other toxic elements in drinking water. Environ Health Persp 117:410–416CrossRefGoogle Scholar
  17. Goldar B, Banerjee N (2004) Impact of informal regulation of pollution on water quality in rivers in India. J Environ Manag 73:117–130CrossRefGoogle Scholar
  18. Gozlan I, Rotstein A, Avisar D (2013) Amoxicillin-degradation products formed under controlled environmental conditions: identification and determination in the aquatic environment. Chemos 91(7):985–992CrossRefGoogle Scholar
  19. Halwani DA, Jurdi M, Abu Salem FK, Jaffa MA, Amacha N, Habib RR, Dhaini HR (2019) Cadmium health risk assessment and anthropogenic sources of pollution in Mount-Lebanon springs. Exposure Health. CrossRefGoogle Scholar
  20. Heberer T (2002) Tracking persistent pharmaceutical residues from municipal sewage to drinking water. J Hydrol 266:175–189CrossRefGoogle Scholar
  21. IGME (1972) Utilización de las aguas subterráneas para la mejora del regadío en la Vega de Granada. Proyecto piloto de utilización de aguas subterráneas para el desarrollo agrícola de la Cuenca del Guadalquivir. Madrid. p 76.Google Scholar
  22. Joseph P, Nandan SB, Adarsh KJ, Anu PR, Varghese R, Sreelekshmi S, Preethy CM, Jayachandran PR, Joseph KJ (2019) Heavy metal contamination in representative surface sediments of mangrove habitats of Cochin. Southern India. Environ Earth Sci 78:490. CrossRefGoogle Scholar
  23. Keshavarzi B, Moore F, Najmeddin A, Rahmani F (2012) The role of selenium and selected trace elements in the etiology of esophageal cancer in high risk Golestan province of Iran. Sci Total Environ 433:89–97CrossRefGoogle Scholar
  24. Kumar M, Ramanathan AL, Tripathi R, Farswan S, Kumar D, Bhattacharya P (2017) A study of trace element contamination using multivariate statistical techniques and health risk assessment in groundwater of Chhaprolaindustrialarea, Gautam Buddha Nagar, Uttar Pradesh, India. Chemosphere 166:135–145CrossRefGoogle Scholar
  25. Kuroda K, Murakami M, Oguma K, Muramatsu Y, Takada H, Takizawa S (2012) Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers. Environ Sci Technol 46:1455–1464CrossRefGoogle Scholar
  26. Li P, Wu J, Qian H, Zhang Y, Yang N, Jing L, Yu P (2016) Hydrogeochemical characterization of groundwater in and around a wastewater irrigated forest in the southeastern edge of the Tengger Desert. Northwest China. Expo Health 8(3):331–348. CrossRefGoogle Scholar
  27. Li P, Tian R, Liu R (2019a) Solute geochemistry and multivariate analysis of water quality in the Guohua Phosphorite Mine, Guizhou Province. China. Expo Health 11(2):81–94. CrossRefGoogle Scholar
  28. Li P, He X, Li Y, Xiang G (2019b) Occurrence and health implication of fluoride in groundwater of loess aquifer in the Chinese Loess Plateau: a case study of Tongchuan. Expo Health 11(2):95–107. CrossRefGoogle Scholar
  29. Liang J, Feng C, Zeng G, Gao X, Zhong M, Li X, Li X, He X, Fang Y (2017) Spatial distribution and source identification of heavy metals in surface soils in a typical coal mine city, Lianyuan, China. Envir Pollution 225:681–690CrossRefGoogle Scholar
  30. Liao F, Wang G, Shi Z, Huang X, Xu F, Xu Q, Guo L (2018) Distributions, sources, and species of heavy metals/trace elements in Shallow groundwater around the Poyang Lake, East China. Expo Health 10:211–227CrossRefGoogle Scholar
  31. Luque-Espinar JA, Chica-Olmo M, Pardo-Igúzquiza E, García-Soldado MJ (2008) Influence of climatological cycles on hydraulic heads across a Spanish aquifer. J Hydrol 354:33–52CrossRefGoogle Scholar
  32. Luque-Espinar JA, Navas N, Chica-Olmo M, Cantero-Malagón S, Chica-Rivas L (2015) Seasonal occurrence and distribution of a group of ECs in the water resources of Granada citymetropolitan areas (SE Spain): pollution of raw drinking water. J Hydrol 531:612–625CrossRefGoogle Scholar
  33. Magesh NS, Chandrasekar N, Elango L (2017) Trace element concentrations in the groundwater of the Tamiraparani river basin, South India: insights from human health risk and multivariate statistical techniques. Chemosphere 185:468–479CrossRefGoogle Scholar
  34. Malchi T, Maor Y, Tadmor G, Shenker M, Chefetz B (2014) Irrigation of root vegetables with treated wastewater: evaluating uptake of pharmaceuticals and the associated human health risks. Environ Sci Technol 48(16):9325–9333CrossRefGoogle Scholar
  35. Mansour F, Mahmoud AH, Walid S et al (2016) Environmental risk analysis and prioritization of pharmaceuticals in a developing world context. Sci Total Environ 557:31–43CrossRefGoogle Scholar
  36. McKinley JM, Ofterdinger U, Young M, Barsby A, Gavin A (2013) Investigating local relationships between trace elements in soils and cancer data. Spatial Stat 5:25–41CrossRefGoogle Scholar
  37. Mitchell E, Frisbie S, Sarkar B (2011) Exposure to multiple metals from groundwater-a global crisis: geology, climate change, health effects, testing, and mitigation. Metallomics 3(9):874–908CrossRefGoogle Scholar
  38. Nakada N, Kirk K, Shinohara H, Harada A, Kuroda K, Takizawa S, Takada H (2008) Evaluation of pharmaceuticals and personal care products as water-soluble molecular markers of sewage. Environ Sci Technol 42:6347–6353CrossRefGoogle Scholar
  39. Pardo-Igúzquiza E, Chica-Olmo M, Luque-Espinar JA, Rodríguez-Galiano V (2015) Compositional cokriging for mapping the probability risk of groundwater contamination by nitrates. Sci Total Environ 532:162–175CrossRefGoogle Scholar
  40. Patil VT, Patil PR (2010) Physicochemical analysis of selected groundwater samples of Amalner town in Jalga on District, Maharashtra, India. J Chem 7:111–116Google Scholar
  41. Rodriguez-Galiano VF, Luque-Espinar JA, Chica-Olmo M, Mendes MP (2018) Feature selection approaches for predictive modelling of ground water nitrate pollution: an evaluation of filters, embedded and wrapper methods. Sci Total Environ 624:661–672CrossRefGoogle Scholar
  42. Santos LHMLM, Araújo AN, Fachini A, Pena A, Delerue-Matos C, Montenegro MCBSM (2010) Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J Hazard Mater 175:45–95CrossRefGoogle Scholar
  43. Schwarzenbach RP, Escher BI, Fenner K, Hofstetter TB, Johnson CA, von Gunten U, Wehrli B (2006) The challenge of micropollutants in aquatic systems. Science 313:1072–1077CrossRefGoogle Scholar
  44. Seiler RL, Zaugg SD, Thomas JM, Howcroft DL (1999) Caffeine and pharmaceuticals as indicators of waste water contamination in wells. Ground Water 37:405–410CrossRefGoogle Scholar
  45. Standley LJ, Rudel RA, Swartz CH, Attfield KR, Christian J, Erickson M, Brody JG (2008) Wastewater-contaminated groundwater as a source of endogenous hormones and pharmaceuticals to surface water ecosystems. Environ Toxicol Chem 27:2457–2468CrossRefGoogle Scholar
  46. Szabo Z, dePaul VT, Fischer JM, Kraemer TF, Jacobsen E (2012) Occurrence and geochemistry of radium in water from principal drinking-water aquifer systems of the United States. Appl Geochem 27:729–752CrossRefGoogle Scholar
  47. Ternes T (2007) The occurrence of micopollutants (sic!) in the aquatic environment: a new challenge for water management. Water Sci Technol 55(12):327–332CrossRefGoogle Scholar
  48. Thuyet DQ, Saito H, Saito T, Moritani S, Kohgo Y, Komatsu T (2016) Multivariate analysis of trace elements in shallow groundwater in Fuchu in western Tokyo Metropolis. Jpn Environ Earth Sci 75:559CrossRefGoogle Scholar
  49. UNESCO (2002) Groundwater contamination inventory. A methodological guide. IHP-VI, series on groundwater, No. 2, p 161Google Scholar
  50. USGS (2011) National water-quality assessment program. Trace elements and radon in groundwater across the United States, 1992–2003. U.S. Department of the Interior, U.S. Geological Survey. Scientific Investigations Report 2011–5059. March 22, 2016
  51. Van Nuijs ALN, Tarcomnicu I, Simons W, Bervoets L, Blust R, Jorens PG, Neels H, Covaci A (2010) Optimization and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the determination of 13 top-prescribed pharmaceuticals in influent wastewater. Anal Bioanal Chem 398(5):2211–2222CrossRefGoogle Scholar
  52. WHO (2002) Water and health in Europe. In: Bartram J, Thyssen N, Gowers K, Lack T (eds) A joint report from the European Environment Agengy and the WHO Regional Office for Europe. WHO Regional Publications, European Seris, No. 93, p 240Google Scholar
  53. WHO (2017) Guidelines for drinking-water quality. Fourth edition incorporating the first addendum. p 631Google Scholar
  54. Wu S, Zhang L, Chen J (2012) Paracetamol in the environment and its degradation by microorganisms. Appl Microbiol Biotechnol 96:875–884CrossRefGoogle Scholar
  55. Wu J, Li P, Qian H, Duan Z, Zhang X (2014) Using correlation and multivariate statistical analysis to identify hydrogeochemical processes affecting the major ion chemistry of waters: Case study in Laoheba phosphorite mine in Sichuan. China. Arab J Geosci 7(10):3973–3982. CrossRefGoogle Scholar
  56. Wu J, Wang L, Wang S, Tian R, Xue C, Feng W, Li Y (2017) Spatiotemporal variation of groundwater quality in an arid area experiencing long-term paper wastewater irrigation, northwest China. Environ Earth Sci 76(13):460. CrossRefGoogle Scholar
  57. Wu J, Li P, Wang D, Ren X, Wei M (2019) Statistical and multivariate statistical techniques to trace the sources and affecting factors of groundwater pollution in a rapidly growing city on the Chinese Loess Plateau. Hum Ecol Risk Assess. CrossRefGoogle Scholar
  58. Zentner E, Gerstl Z, Weisbrod N, Lev O, Pankratov I, Russo D, Gasser G, Voloshenko-Rosin A, Ronen D (2015) Deep penetration of pharmaceuticals and personal care products through the vadose zone of effluent-irrigated land. Vadose Zone J. CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Geological Survey of Spain (IGME)GranadaSpain
  2. 2.Department of GeodinamycsUniversity of GranadaGranadaSpain

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