Rosai–Dorfman disease and left ventricular noncompaction cardiomyopathy: A heart failure conundrum
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The principles, Hickam’s dictum and Occam’s razor, have existed in counterbalance, guiding a physician’s diagnostic approach together for decades. Although Occam’s razor implores one to favor theories or hypotheses with the least amount of assumptions, there are often times a patient’s ailment may be better attributed to multiple co-existing problems. The latter was well understood by the late John Hickam, MD, who is credited to have famously stated: “A man can have as many diseases as he damn well pleases.” These two philosophical paradigms clashed; in this case, we present of a 19-year-old male who initially was seen for acute epigastric pain, quickly decompensated into cardiogenic shock, and was subsequently diagnosed with two extraordinarily rare diseases in Rosai–Dorfman disease (RDD) and left ventricular noncompaction cardiomyopathy (LVNC). While in the last decade the data regarding LVNC have flourished, there is still scant literature reporting RDD, especially...
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This case report did not have reportable results.
There are no financial or nonfinancial competing interests for this report.
This was not a study using human participants, human data or tissue.
The individual’s data was not used in this case report.
MPL and AD have contributed towards the drafting of this report.
- 3.Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entitiy. Arch Pathol 1969;87:63–70.Google Scholar
- 8.Ganitonde S. Multofical, extranodal sinus hisitocytosis with massive lymphadenopathy: An overview. Arch Pathol Lab Med 2007;131:1117–21.Google Scholar
- 11.Maron BJ, Towbin AJ, Thiene G, Antzelevitch C, Corrado D, Arnett D, et al. Contemporary definitions and classifications of the cardiomyopathies: An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 2006;113:1807–16.CrossRefGoogle Scholar
- 14.Pfammatter JP, Paul T, Flik J, Drescher J, Kallfelz HC. Q-fever associated myocarditis in a 14-year-old boy. Z Kardiol 1995;84:947.Google Scholar