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The role of multimodality imaging in takotsubo cardiomyopathy

  • Review Article
  • Published:
Journal of Nuclear Cardiology Aims and scope

Abstract

Takotsubo cardiomyopathy (TC) is a syndrome of transient left ventricular (LV) dysfunction mimicking acute coronary syndrome. Although the mechanisms underlying the occurrence of TC are unknown, several imaging techniques contribute to its diagnosis. Here we review the current knowledge about TC, in particular, the pathophysiology and the role of imaging including nuclear cardiovascular medicine.

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Abbreviations

123I-BMIPP:

Iodine-123-labeled beta-methyl-P-iodophenylpentadecanoic acid

123I-MIBG:

Iodine-123-labeled metaiodobenzylguanidine

18F-FDG:

Fluorine-18-labeled fluorodeoxyglucose

ACS:

Acute coronary syndrome

AR:

Adrenergic receptor

CBF:

Cerebral blood flow

CFR:

Coronary flow reserve

CMR:

Cardiovascular magnetic resonance

ECG:

Electrocardiography

LV:

Left ventricle/ventricular

EF:

Ejection fraction

MBF:

Myocardial blood flow

PET:

Positron emission tomography

SPECT:

Single-photon emission computed tomography

TC:

Takotsubo cardiomyopathy

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Acknowledgments

We thank Mitsunori Ohtsubo and Eriko Suzuki for their support.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Hokkaido University of Graduate School of Medicine, Kita 15 Nishi 7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan

    Osamu Manabe MD, PhD

  2. Department of Cardiovascular Medicine, Hokkaido University of Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan

    Masanao Naya MD, PhD & Kazuhiro Koyanagawa MD

  3. Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan

    Noriko Oyama-Manabe MD, PhD

  4. Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Nagara Tamaki MD, PhD

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  1. Osamu Manabe MD, PhD
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Correspondence to Masanao Naya MD, PhD.

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Manabe, O., Naya, M., Oyama-Manabe, N. et al. The role of multimodality imaging in takotsubo cardiomyopathy. J. Nucl. Cardiol. 26, 1602–1616 (2019). https://doi.org/10.1007/s12350-018-1312-x

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