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Journal of Nuclear Cardiology

, Volume 26, Issue 1, pp 318–323 | Cite as

Quantification of myocardial blood flow and myocardial flow reserve with SPECT imaging technique

  • Thet KhaingEmail author
  • Ching Chiew Wong Raymond
  • Wan Xian Chan
  • Chen Hao
  • Siong Sung Wong
Images that Teach

Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is an established imaging technique to assess for myocardial ischemia, infarction, and viability. However, the technique still has its weakness where the balanced myocardial ischemia in the setting of multi-vessels coronary artery disease can be missed. Recently, there is revolutionary development in the field of the Nuclear Cardiology whereby the quantification of myocardial blood flow (MBF) and myocardial flow reserve (MFR) with an innovative Tc-99m Sestamibi dynamic-SPECT method had been established using solid-state gamma camera.1 The quantification of the myocardial blood flow and myocardial flow reserve can be used to exclude balanced myocardial ischemia and to assess microvascular dysfunction where it is shown to be of great prognostic value.2,3

In this Images That Teach, we are presenting three cases: transmural infarct with inducible myocardial ischemia in patients with triple vessel coronary...

Notes

Disclosure

Thet Khaing, Ching Chiew Wong Raymond, Wan Xian Chan, Chen Hao, and Siong Sung Wong have no conflicts of interest to declare.

References

  1. 1.
    Slomka P, Berman DS, Germano G. Myocardial blood flow from SPECT. J Nucl Cardiol 2017;24(1):278-81.CrossRefGoogle Scholar
  2. 2.
    Ziadi MC, deKemp RA, Williams KA, Guo A, Chow BJW, Renaud JM, et al. Impaired myocardial flow reserve on rubidium-82 positron emission tomography imaging predicts adverse outcomes in patients assessed for myocardial ischemia. J Am Coll Cardiol 2011;58:740-8.CrossRefGoogle Scholar
  3. 3.
    Murthy VL, Naya M, Foster CR, Hainer J, Gaber M, Carli GD, et al. Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. Circulation 2011;124:2215-24.CrossRefPubMedCentralGoogle Scholar

Copyright information

© American Society of Nuclear Cardiology 2018

Authors and Affiliations

  • Thet Khaing
    • 1
    Email author
  • Ching Chiew Wong Raymond
    • 1
  • Wan Xian Chan
    • 1
  • Chen Hao
    • 2
  • Siong Sung Wong
    • 1
  1. 1.Cardiology DepartmentNational University Heart CentreSingaporeSingapore
  2. 2.Department of Diagnostic ImagingNational University HospitalSingaporeSingapore

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