Quantification of myocardial blood flow and myocardial flow reserve with SPECT imaging technique
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Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is an established imaging technique to assess for myocardial ischemia, infarction, and viability. However, the technique still has its weakness where the balanced myocardial ischemia in the setting of multi-vessels coronary artery disease can be missed. Recently, there is revolutionary development in the field of the Nuclear Cardiology whereby the quantification of myocardial blood flow (MBF) and myocardial flow reserve (MFR) with an innovative Tc-99m Sestamibi dynamic-SPECT method had been established using solid-state gamma camera.1 The quantification of the myocardial blood flow and myocardial flow reserve can be used to exclude balanced myocardial ischemia and to assess microvascular dysfunction where it is shown to be of great prognostic value.2,3
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Disclosure
Thet Khaing, Ching Chiew Wong Raymond, Wan Xian Chan, Chen Hao, and Siong Sung Wong have no conflicts of interest to declare.
References
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