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Journal of Nuclear Cardiology

, Volume 25, Issue 3, pp 1029–1036 | Cite as

Validation of cadmium–zinc–telluride camera for measurement of left ventricular systolic performance

  • Elisabeth CoupezEmail author
  • Charles Merlin
  • Viateur Tuyisenge
  • Laurent Sarry
  • Bruno Pereira
  • Jean René Lusson
  • Louis Boyer
  • Lucie Cassagnes
Original Article

Abstract

Background

There are paucity of data comparing measurements of left ventricular systolic performance using cadmium–zinc–telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging.

Methods

60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement.

Results

48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques.

Conclusions

CZT-SPECT is reliable for LVEF measurement.

Key Words

Echocardiography magnetic resonance imaging myocardial perfusion imaging SPECT left ventricular function myocardial infarction 

Abbreviations

LVEF

Left ventricular ejection fraction

CMR

Cardiac magnetic resonance imaging

CZT-SPECT

Cadmium-zinc-telluride Spectrum Dynamics D-SPECT®

EDV

End diastolic volume

ESV

End systolic volume

WM

Wall motion

WT

Wall thickening

Echo

Echocardiography

MI

Myocardial infarction

MPI

Myocardial perfusion imaging

Notes

Disclosure

The authors of this manuscript have no conflict of interest to declare.

Supplementary material

12350_2017_816_MOESM1_ESM.doc (32 kb)
Supplementary material 1 (DOC 32 kb)
12350_2017_816_MOESM2_ESM.docx (17 kb)
Supplementary material 2 (DOCX 16 kb)
12350_2017_816_MOESM3_ESM.doc (29 kb)
Supplementary material 3 (DOC 29 kb)
12350_2017_816_MOESM4_ESM.pptx (1.1 mb)
Supplementary material 4 (PPTX 1101 kb)

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Copyright information

© American Society of Nuclear Cardiology 2017

Authors and Affiliations

  • Elisabeth Coupez
    • 1
    Email author
  • Charles Merlin
    • 2
  • Viateur Tuyisenge
    • 3
  • Laurent Sarry
    • 3
  • Bruno Pereira
    • 4
  • Jean René Lusson
    • 1
  • Louis Boyer
    • 5
  • Lucie Cassagnes
    • 5
  1. 1.Department of CardiologyCHU Gabriel MontpiedClermont-FerrandFrance
  2. 2.Nuclear Medicine DepartmentJean Perrin Cancer CenterClermont-FerrandFrance
  3. 3.ISIT, UMR CNRS 6284Université d’Auvergne Clermont1Clermont-FerrandFrance
  4. 4.DRCICHU Gabriel MontpiedClermont-FerrandFrance
  5. 5.Department of RadiologyCHU Gabriel MontpiedClermont-FerrandFrance

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