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Journal of Nuclear Cardiology

, Volume 23, Issue 6, pp 1514–1517 | Cite as

‘Hot spot’ cardiac ischemia imaging with fluorodeoxyglucose positron emission tomography

  • Marissa T. Ferguson
  • Andrew Mallia
  • Kenneth Yap
  • Samuel Wright
  • Rodney J. Hicks
  • Michael S. Hofman
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We present two cases of myocardial ischemia diagnosed incidentally at the time of oncologic 18F-fluorodeoxyglucose positron emission tomography (FDG PET) imaging. These cases highlight the potential of FDG PET cardiac metabolic imaging to detect acute or recent myocardial ischemia. When reporting oncological FDG PET/CT staging studies, it is important to differentiate focal and intense myocardial uptake in a vascular distribution from physiologic uptake, which is usually less intense, more heterogeneous and does not conform to a coronary territory.

Case 1A gentleman in his sixties was referred for FDG PET/CT staging of a locally invasive mesothelioma involving the right hemithorax. While acquiring the scan, he suffered a cardiac arrest due to ventricular fibrillation requiring resuscitation. Upon review of the FDG PET/CT images, intense and well-demarcated FDG uptake was noted in the anterior, anteroseptal and apical left ventricular myocardial wall, suggestive of left anterior...

Keywords

Left Anterior Descend Chronic Total Occlusion Myocardial Uptake Left Anterior Descend Artery Left Anterior Descend Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Authors’ contributions

MTF and AM drafted the manuscript and were involved in critically revising the manuscript for important intellectual content. KY, SW, RJH, and MSH were involved in critically revising the manuscript for important intellectual content. All authors have read and approved the final manuscript.

Disclosures

Dr Marissa Ferguson has received research grants from the Australian and New Zealand College of Anaesthetists and the MIGA insurance group. There are no other disclosures or conflicts of interest to declare.

References

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    He ZX, Shi RF, Wu YJ, Tian YQ, Liu XJ, Wang SW, et al. Direct imaging of exercise-induced myocardial ischemia with fluorine-18-labeled deoxyglucose and Tc-99m-sestamibi in coronary artery disease. Circulation 2003;108:1208–13.CrossRefPubMedGoogle Scholar
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    Arun S, Mittal BR, Bhattacharya A, Rohit MK. Comparison of Tc-99m tetrofosmin myocardial perfusion scintigraphy and exercise F18-FDG imaging in detection of myocardial ischemia in patients with coronary artery disease. J Nucl Cardiol 2014;22:98–100.CrossRefPubMedGoogle Scholar

Copyright information

© American Society of Nuclear Cardiology 2016

Authors and Affiliations

  • Marissa T. Ferguson
    • 1
  • Andrew Mallia
    • 2
  • Kenneth Yap
    • 3
  • Samuel Wright
    • 4
  • Rodney J. Hicks
    • 2
    • 5
  • Michael S. Hofman
    • 2
    • 5
  1. 1.Department of AnaesthesiaPeter MacCallum Cancer CentreMelbourneAustralia
  2. 2.Centre for Molecular ImagingPeter MacCallum Cancer CentreMelbourneAustralia
  3. 3.Department of Nuclear MedicineAlfred HospitalMelbourneAustralia
  4. 4.Department of CardiologyPeter MacCallum Cancer CentreMelbourneAustralia
  5. 5.Department of MedicineUniversity of MelbourneParkvilleAustralia

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