Prevention of diet-induced obesity in C57BL/BJ mice with addition of 2 % dietary green tea but not with cocoa or coffee to a high-fat diet

  • S. A. Cichello
  • D. P. Begg
  • M. Jois
  • R. S. Weisinger
Original Article


Most of the fat oxidation effects of green tea have been observed in a beverage form. This study explored the use of green tea as feed formation in obese mice to protect against diet-induced obesity. Forty-eight adult C57BL/6J mice were randomised to either a control diet with 36.1 % w/w sucrose or a standard diet, except for the replacement of 2 % w/w of the sucrose dietary component (36.1 % sucrose in control) with 2 % w/w cocoa (34.1 % sucrose), 2 % w/w coffee, or 2 % w/w powdered Japanese green tea. At 16th week, body composition, plasma glucose, organ samples and bone mineral density were obtained. In comparison to the control group, only the 2 % green tea group displayed lower body weight (p < 0.01), body fat, liver weight (p < 0.05), hepatic lipid status and higher lean mass. The coffee group displayed lower body fat (p < 0.05) and the cocoa group lower plasma glucose (p < 0.05), but this was not substantiated by other parameters. Results of study indicate the anti-obesity potential of green tea when consumed as 2 % (w/w %) of the diet probably by lipolysis and decreased systemic inflammation resulting from consumption of a high-fat, high-sucrose diet in obesity-prone strain of mice.


Green tea Caffeine Diet-induced obesity EGCG Catechins 


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Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  • S. A. Cichello
    • 1
    • 3
  • D. P. Begg
    • 2
  • M. Jois
    • 1
  • R. S. Weisinger
    • 2
  1. 1.School of Life SciencesLa Trobe UniversityMelbourneAustralia
  2. 2.School of Psychological SciencesLa Trobe UniversityBundooraAustralia
  3. 3.Key State Laboratory for Pu-erh Tea ResearchYunnan Agricultural UniversityYunnanPeople’s Republic of China

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