Distal intestinal obstructive syndrome (DIOS): a gastrointestinal complication of cystic fibrosis in adults

  • Marianna MaviliaEmail author
Case Report


Distal intestinal obstructive syndrome (DIOS) is a gastrointestinal complication of cystic fibrosis caused by increased viscosity of intraluminal contents leading to partial or complete bowel obstruction. DIOS is often misdiagnosed or mistaken for surgical bowel obstruction or appendicitis. This can lead to unnecessary surgical intervention when DIOS should be treated medically with aggressive bowel regimen. The aim of this report is to present a case of a young female with cystic fibrosis presenting with DIOS and discuss the clinical recognition and management of DIOS.


Distal intestinal obstructive syndrome Bowel obstruction Cystic fibrosis 


Compliance with ethical standards

Conflict of interest

Author has no financial conflicts of interest related to this work.

Human and animal rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

Informed consent was obtained from all patients for being included in the study.


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Copyright information

© Japanese Society of Gastroenterology 2019

Authors and Affiliations

  1. 1.Department of MedicineUniversity of ConnecticutFarmingtonUSA

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