Treatment of gastric metastases from renal cell carcinoma with endoscopic therapy
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Gastric metastases from renal cell carcinoma (RCC) are rare with few cases described in the literature.
We report the history of a 77-year-old male patient who underwent a right radical nephrectomy because of RCC. Two years after the diagnosis, he presented with abdominal pain and evidence of upper gastrointestinal bleeding. Esophagogastroduodenoscopy revealed a 3 cm, ulcerated, pedunculated polypoid mass in the stomach that was removed with a diathermic snare. Histology with immunohistochemistry confirmed the diagnosis of metastatic RCC. Three months of follow-up revealed no further episode of rebleeding.
We identified (using the PubMed database) 44 cases of gastric metastasis of RCC in the literature; the majority were male patients, with mean age at presentation of 67.2 years and average time from nephrectomy to presentation of gastric metastases of 6.9 years. Our results suggest that endoscopy may have an important role in the treatment of these patients for controlling the complications and/or improving mean survival time.
Gastric metastases of RCC are rare but should be considered even many years after diagnosis and treatment of RCC, particularly in patients with gastrointestinal symptoms.
KeywordsRenal cell carcinoma Gastric metastases Upper gastrointestinal bleeding Endoscopic treatment
Conflict of Interest: The authors have nothing to declare.
Human/Animal Rights: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).
Informed Consent: Informed consent was obtained from the patient to be included in the study.
- 1.Campbell SC, Andrew CN. Renal tumours. In: Wein AJ, Kavoussi LR, Novick AC, et al., editors. Campbell-Walsh urology. 9th ed. Saunders Elsevier Pub; 2007. p. 1582–605.Google Scholar
- 5.Nakamura R, Shimada A, Hara Y, et al. One case of intussusception due to intestinal metastasis of renal carcinoma. Jpn J Clin Surg. 1984;43:1637–40.Google Scholar
- 6.Cosme A, Orive V, Alzate LF, Torrado J, et al. Metástasis gástrica de un hipernefroma. Gastroenterol Hepatol. 1984;7:400–1.Google Scholar
- 7.Bisesti V, Parrella E, Cataldi C, et al. Ser di un raro caso di metastasi gastrica di adenocarcinoma renale. Osp Ital Pediatr. 1984;19:609–20.Google Scholar
- 11.Otawa T, Muto I. A case of synchronous gastric metastasis from renal cell carcinoma with the chief complaint of hematemesis. Jpn J Clin Surg. 1992;53:1219–22.Google Scholar
- 27.Ko WO, Yang US, Kim NS, et al. A case of a gastric metastasis of a renal cell carcinoma. Korean J Gastrointest Endosc. 2008;36:288–91.Google Scholar