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Clinical Journal of Gastroenterology

, Volume 7, Issue 2, pp 148–154 | Cite as

Treatment of gastric metastases from renal cell carcinoma with endoscopic therapy

  • Herculano RitaEmail author
  • Alves Isabel
  • Chapim Iolanda
  • Hann Alexander
  • Costa Pedro
  • Carvalho Liliana
  • Monteiro Lucília
  • Santos Sofia
  • Matos Leopoldo
Case Report

Abstract

Introduction

Gastric metastases from renal cell carcinoma (RCC) are rare with few cases described in the literature.

Case report

We report the history of a 77-year-old male patient who underwent a right radical nephrectomy because of RCC. Two years after the diagnosis, he presented with abdominal pain and evidence of upper gastrointestinal bleeding. Esophagogastroduodenoscopy revealed a 3 cm, ulcerated, pedunculated polypoid mass in the stomach that was removed with a diathermic snare. Histology with immunohistochemistry confirmed the diagnosis of metastatic RCC. Three months of follow-up revealed no further episode of rebleeding.

Discussion

We identified (using the PubMed database) 44 cases of gastric metastasis of RCC in the literature; the majority were male patients, with mean age at presentation of 67.2 years and average time from nephrectomy to presentation of gastric metastases of 6.9 years. Our results suggest that endoscopy may have an important role in the treatment of these patients for controlling the complications and/or improving mean survival time.

Conclusion

Gastric metastases of RCC are rare but should be considered even many years after diagnosis and treatment of RCC, particularly in patients with gastrointestinal symptoms.

Keywords

Renal cell carcinoma Gastric metastases Upper gastrointestinal bleeding Endoscopic treatment 

Notes

Disclosures

Conflict of Interest: The authors have nothing to declare.

Human/Animal Rights: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).

Informed Consent: Informed consent was obtained from the patient to be included in the study.

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Copyright information

© Springer Japan 2014

Authors and Affiliations

  • Herculano Rita
    • 1
    Email author
  • Alves Isabel
    • 1
  • Chapim Iolanda
    • 1
  • Hann Alexander
    • 2
  • Costa Pedro
    • 1
  • Carvalho Liliana
    • 1
  • Monteiro Lucília
    • 3
  • Santos Sofia
    • 1
  • Matos Leopoldo
    • 1
  1. 1.Department of GastroenterologyEgas Moniz Hospital, Ocidental Lisbon Hospitalar CenterLisbonPortugal
  2. 2.Department of Internal Medicine and GastroenterologyKatharinen HospitalStuttgartGermany
  3. 3.Department of PathologyEgas Moniz Hospital, Ocidental Lisbon Hospitalar CenterLisbonPortugal

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