Clinical Journal of Gastroenterology

, Volume 6, Issue 2, pp 134–138 | Cite as

Primary squamous cell carcinoma of the liver concomitant with primary colon cancer: report of a case

  • Kiyoto Morito
  • Keita Kai
  • Atsushi Miyoshi
  • Hiroshi Kubo
  • Takao Ide
  • Shinya Azama
  • Hiroyuki Irie
  • Yasuo Koga
  • Kenji Sumi
  • Osamu Ikeda
  • Kenji Kitahara
  • Hirokazu Noshiro
Case Report


A 55-year-old Japanese female was admitted to our hospital to treat colon cancer. Computed tomography revealed a 2.6 × 2.0 cm liver mass considered to be liver metastasis. She synchronously underwent right colectomy with D3 lymph node dissection and subsegmentectomy 8 under the diagnosis of advanced colon cancer with liver metastasis. The pathology examination revealed the liver nodule was pure squamous cell carcinoma (SCC), whereas histology of colon cancer was a well differentiated tubular adenocarcinoma containing no squamous component. The patient underwent intensive checkup by imaging for a primary site of SCC. However, no lesion considered as possible primary site of SCC was found. Therefore, the liver nodule was finally diagnosed as a primary hepatic SCC. Primary SCC of the liver is a rare and high-grade malignant tumor. Recurrent multiple liver nodule was found at 13 months after surgery and the patient died of cancer 17 months after surgery.


Primary liver cancer Squamous cell carcinoma Adenosquamous carcinoma Colon cancer Double cancer 



We would like to thank the Dr. Osamu Nakashima (Department of Pathology, Kurume University), for valuable comments for pathological diagnosis.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Japan 2013

Authors and Affiliations

  • Kiyoto Morito
    • 1
  • Keita Kai
    • 2
  • Atsushi Miyoshi
    • 1
  • Hiroshi Kubo
    • 1
  • Takao Ide
    • 1
  • Shinya Azama
    • 3
  • Hiroyuki Irie
    • 3
  • Yasuo Koga
    • 1
  • Kenji Sumi
    • 1
  • Osamu Ikeda
    • 1
  • Kenji Kitahara
    • 1
  • Hirokazu Noshiro
    • 1
  1. 1.Department of SurgerySaga University Faculty of MedicineSagaJapan
  2. 2.Department of Pathology and MicrobiologySaga University Faculty of MedicineSagaJapan
  3. 3.Department of RadiologySaga University Faculty of MedicineSagaJapan

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