Advertisement

Clinical Journal of Gastroenterology

, Volume 2, Issue 3, pp 156–160 | Cite as

Protein-losing enteropathy, deep venous thrombosis and pulmonary embolism in a patient with generalized inflammatory polyposis in remission stage of ulcerative colitis

  • Yoshiaki KawaguchiEmail author
  • Tetsuya Mine
  • Ichiro Kawana
  • Satoshi Umemura
Case Report
  • 163 Downloads

Abstract

We experienced a patient with severe protein-losing enteropathy and generalized inflammatory polyposis. In addition, this case was complicated by deep venous thrombosis and pulmonary embolism. Patients with inflammatory bowel disease are at increased risk for thromboembolic events, most commonly in the setting of active colitis. However, our patient was in the remission stage. We report the occurrence of deep venous thrombosis and pulmonary embolism as a complication of inflammatory polyposis and protein-losing enteropathy in the remission stage of ulcerative colitis.

Keywords

Protein-losing enteropathy Deep venous thrombosis Pulmonary embolism Inflammatory polyposis Ulcerative colitis 

References

  1. 1.
    Kelly JK, Gabos S. The pathogenesis of inflammatory polyps. Dis Colon Rectum. 1987;30:251–4.CrossRefPubMedGoogle Scholar
  2. 2.
    Jaran KN, Sircus W, Walker RJ, et al. Pseudopolyposis in ulcerative colitis. Lancet. 1969;1:555–9.Google Scholar
  3. 3.
    Kelly JK, Langevin JM, Price LM, et al. Giant and symptomatic inflammatory polyps of the colon in idiopathic inflammatory bowel disease. Am J Surg Pathol. 1986;10:420–8.CrossRefPubMedGoogle Scholar
  4. 4.
    Talbot RW, Heppell J, Dozois RR, Beart RW. Vascular complications of inflammatory bowel disease. Mayo Clin Proc. 1986;61:140–5.CrossRefPubMedGoogle Scholar
  5. 5.
    Fitterer JD, Cromwell LG, Sims JE. Colonic obstruction by giant pseudopolyposis. Gastroenterology. 1977;72:153–6.PubMedGoogle Scholar
  6. 6.
    Heinrichs HR, Goldman H. Localized giant pseudopolyps of the colon. JAMA. 1968;205:248–9.CrossRefGoogle Scholar
  7. 7.
    Waldmann TA. Protein-losing enteropathy. Gastroenterology. 1966;50:422–33.PubMedGoogle Scholar
  8. 8.
    Steinfeld JL, Davidson JD, Gordon RS Jr, et al. Mechanism of hypoproteinemia in patients with regional enteritis and ulcerative colitis. Am J Med. 1960;29:405–15.CrossRefPubMedGoogle Scholar
  9. 9.
    Bryan RL, Newman J, Alexander-Williams J. Giant inflammatory polyposis in ulcerative colitis presenting with protein losing enteropathy. J Clin Pathol. 1990;43:346–7.CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Koga H, Iida M, Aoyagi K, et al. Generalized giant inflammatory polyposis in a patient with ulcerative colitis presenting with protein-losing enteropathy. Am J Gastroenterol. 1995;90:829–31.PubMedGoogle Scholar
  11. 11.
    Conlan MG, Haire WD, Burnett DA. Prothrombotic abnormalities in inflammatory bowel disease. Dig Dis Sci. 1989;34:1089–93.CrossRefPubMedGoogle Scholar
  12. 12.
    Oshitani N, Moriyama Y, Matsumoto T, Kobayashi K, Kitano A. Protein-losing enteropathy from cap polyposis. Lancet. 1995;346:1567.CrossRefPubMedGoogle Scholar
  13. 13.
    Anderson R, Kaariainen IT, Hanauer SB. Protein-losing enteropathy and massive pulmonary embolism in a patient with giant inflammatory polyposis and quiescent ulcerative colitis. Am J Med. 1996;101:323–5.CrossRefPubMedGoogle Scholar
  14. 14.
    Kobayashi K, Hamada Y, Serizawa H, Watanabe N, Tsuchimoto K. A case report of ulcerative colitis complicated with protein losing enteropathy and colon cancer in a young female (in Japanese with English abstract). Nippon Shokakibyou Gakkai Zasshi. 1997;94:772–7.Google Scholar
  15. 15.
    Harris RC, Ismail N. Extrarenal complications of the nephritic syndrome. Am J Kidney Dis. 1994;23:477–97.CrossRefPubMedGoogle Scholar
  16. 16.
    Vaezi MF, Rustagi PK, Elson CO. Transient protein S deficiency associated with cerebral venous thrombosis in active ulcerative colitis. Am J Gastroenterol. 1995;90:313–5.PubMedGoogle Scholar

Copyright information

© Springer 2009

Authors and Affiliations

  • Yoshiaki Kawaguchi
    • 1
    Email author
  • Tetsuya Mine
    • 1
  • Ichiro Kawana
    • 2
  • Satoshi Umemura
    • 2
  1. 1.Department of GastroenterologyTokai University School of MedicineIseharaJapan
  2. 2.Second Department of Internal MedicineYokohama City University School of MedicineKanazawa-kuJapan

Personalised recommendations