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Clinical Journal of Gastroenterology

, Volume 1, Issue 4, pp 145–147 | Cite as

Granulocytic sarcoma presenting as a thrombosed external hemorrhoid in a patient with myelodysplastic syndrome overt leukemia

  • Tadataka HayashiEmail author
  • Toshio Nakamura
  • Satoki Nakamura
  • Kiyotaka Kurachi
  • Atsuko Fukazawa
  • Koichi Nakamura
  • Akihito Nakajima
  • Shohachi Suzuki
  • Hiroyuki Konno
Case Report
  • 87 Downloads

Abstract

A 67-year-old Japanese man complained of a painful lump in his anus. He had a 15-month history of myelodysplastic syndrome (MDS) and had been diagnosed with MDS overt leukemia. A solid lump measuring 1.0 cm in diameter was detected in the anal verge. Under a diagnosis of a thrombosed external hemorrhoid, thrombectomy was performed under local anesthesia. One week after thrombectomy, the wound had not healed, and grayish-green tissue was seen at the bottom. A biopsy of the wound revealed atypical mononuclear cell infiltration. Myeloperoxidase and lysozyme were positive on immunohistochemical staining. Finally, the diagnosis of granulocytic sarcoma (GS) was made. Though it is well known that perianal complications occur quite often in patients with leukemia, it is unusual for a diagnosis of GS of the anus to be definitely established. To our knowledge, there has not been a previous report of GS presenting as a thrombosed external hemorrhoid. The development of GS should be considered during the management of such lesions, especially in patients with bone marrow disorders, such as acute myeloid leukemia (AML) or high-risk MDS.

Keywords

Granulocytic sarcoma (GS) Hemorrhoid Myelodysplastic syndromes (MDS) Acute myeloid leukemia (AML) 

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Copyright information

© Springer 2008

Authors and Affiliations

  • Tadataka Hayashi
    • 1
    Email author
  • Toshio Nakamura
    • 1
  • Satoki Nakamura
    • 2
  • Kiyotaka Kurachi
    • 1
  • Atsuko Fukazawa
    • 1
  • Koichi Nakamura
    • 1
  • Akihito Nakajima
    • 1
  • Shohachi Suzuki
    • 1
  • Hiroyuki Konno
    • 1
  1. 1.Second Department of SurgeryHamamatsu University School of MedicineHamamatsuJapan
  2. 2.Department of HematologyHamamatsu University School of MedicineHamamatsuJapan

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