The Cerebellum

, Volume 15, Issue 1, pp 26–29 | Cite as

Non-Ataxic Presenting Symptoms of Dominant Ataxias

Review
First Online:

Abstract

While the onset of a dominantly inherited ataxia is typically taken to be the onset of gait ataxia, a wide range of other symptoms related to central and/or peripheral nervous system impairment, or even to non-neurological involvement, can be the presenting feature. Knowledge of these is fairly robust for the commonest spinocerebellar ataxias (SCAs 1, 2, 3 and 6) and for those where a striking non-ataxic presentation is the norm (SCAs 7 and 12), but the literature is potentially misleading in the rarer dominant ataxias. This review summarises what is currently known of these non-ataxic presentations and outlines and explains the difficulties associated with determining non-ataxic presentations of dominant ataxias. The relevant literature was surveyed, including systematic reviews (where available) and case reports. Non-ataxic presentations of dominant ataxias are classified by symptom.

Keywords

Spinocerebellar ataxias SCAs Dominant ataxias Clinical presentation 
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Notes

Conflict of Interest

The author declares no conflict of interest for this submission.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Medicine (Neuroscience)Monash UniversityMelbourneAustralia
  2. 2.Department of NeuroscienceAlfred HospitalMelbourneAustralia

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