“Brainstem Cognitive Affective Syndrome” Following Disruption of the Cerebrocerebellar Network
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Insights into the role of the cerebellum in nonmotor behavioural, cognitive and affective processes have expanded during the last decades to an exciting area of innovative research across disciplines. Indeed, recent advances in the understanding of the reciprocal neuroanatomical connections between the infratentorial structures and the nonmotor supratentorial regions, combined with evidence from functional neuroimaging studies, neurophysiological research data and clinical neuropsychological findings substantially extended the traditional view of the cerebellum as a sole coordinator of autonomic and somatic motor function to that of a crucial modulator of neurocognition and affect . By contrast, possible involvement of the brainstem in cognitive and affective processing received only little attention.
In a series of influential studies, Schmahmann et al. integrated evidence from different strands of clinical and experimental research on the cerebellum and concluded that...
KeywordsTrail Make Test Frontal Assessment Battery Anosognosia Trail Make Test Part Cerebellar Cognitive Affective Syndrome
This research was supported by Strategic Research Program 15 (SPR15), awarded by the Vrije Universiteit Brussel, Belgium.
Conflict of Interest
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