The Cerebellum

, Volume 13, Issue 4, pp 531–535 | Cite as

Late-Onset Obsessive-Compulsive Disorder Associated with Left Cerebellar Lesion

  • Matteo Tonna
  • Rebecca Ottoni
  • Paolo Ossola
  • Chiara De Panfilis
  • Carlo Marchesi
Case Report


The onset of obsessive-compulsive disorder (OCD) after age 50 is rare and generally related to an organic etiology. An involvement of fronto-striatal circuits has been strongly suggested, whereas cerebellum remains so far scarcely explored. We present here the description of a “pure” late-onset OCD associated with a cerebellar lesion, neither comorbid with other mental disorders nor with neurological syndromes. To our knowledge, this condition was not previously described in literature. The patient is a 62-year-old woman who developed a late-onset OCD associated with a left cerebellar lesion due to an arachnoid cyst in the left posterior fossa. We debate the possible role of the cerebellar lesion in favoring a transition from a predisposing liability (namely an obsessive-compulsive personality disorder and a depressive status) to the onset of OCD in this woman.


Obsessive-compulsive disorder (OCD) Obsessive-compulsive personality disorder (OCPD) Depression Cerebellum Arachnoid cyst 



The authors would like to thank Dr. Laura Cucurachi, Dr. Francesca Ormitti, and Dr. Giorgio Baldari for their important contribution in neurological and neuroimaging aspects of the present case report.

Conflict of Interest

No authors received funding for the research and had financial involvement that could represent potential conflicts of interest.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Matteo Tonna
    • 2
  • Rebecca Ottoni
    • 1
  • Paolo Ossola
    • 1
  • Chiara De Panfilis
    • 1
  • Carlo Marchesi
    • 1
    • 3
  1. 1.Department of Neuroscience, Psychiatric UnitUniversity of ParmaParmaItaly
  2. 2.Mental Health DepartmentLocal Health ServiceParmaItaly
  3. 3.Dipartimento di Neuroscienze, Unità di Psichiatria, Ospedale-Padiglione BragaUniversità di ParmaParmaItaly

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