Journal of Hematopathology

, Volume 12, Issue 1, pp 25–26 | Cite as

Nodal mesenteric marginal zone lymphoma with amyloid deposits, calcification, and ossification

  • Sotiris SotiriouEmail author
  • Triantafyllia Koletsa
  • Sofia-Eleni Tzorakoleftheraki
  • Vassiliki Kotoula
  • Stylianos Mantalovas
  • Ioannis Kostopoulos


Marginal zone lymphomas (MZLs) are rarely associated with amyloid deposits, calcification, and ossification. Herein, we describe a case of a MZL with a primary nodal mesenteric presentation, associated with amyloid deposits, calcification, and ossification, highlighting its clinicopathological features, based on our findings, but also on a brief review of the literature.


Marginal zone lymphoma Calcification Ossification Amyloid deposits 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K (2016) Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: a clinicopathologic study of 5 cases. Pathol Res Pract 212(3):185–189CrossRefGoogle Scholar
  2. 2.
    Grogg KL, Aubry M-C, Vrana JA, Theis JD, Dogan A (2013) Nodular pulmonary amyloidosis is characterized by localized immunoglobulin deposition and is frequently associated with an indolent B-cell lymphoproliferative disorder. Am J Surg Pathol 37(3):406–412CrossRefGoogle Scholar
  3. 3.
    Xiang H, Wu Z, Wang Z, Yao H (2015) Nodular pulmonary amyloidosis and obvious ossification due to primary pulmonary MALT lymphoma with extensive plasmacytic differentiation: report of a rare case and review of the literature. Int J Clin Exp Pathol 8(6):7482–7487Google Scholar
  4. 4.
    Haas BD, Margo CE (2007) Orbital lymphoma, amyloid, and bone. Ophthalmology 114(6):5–7CrossRefGoogle Scholar
  5. 5.
    Urban BA, Fishman EK, Goldman SM, Scott WW Jr, Jones B, Humphrey RL, Hruban RH (1993) CT evaluation of amyloidosis: spectrum of disease. RadioGraphics 13(6):1295–1308CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Pathology Department, Faculty of MedicineAristotle University of ThessalonikiThessalonikiGreece
  2. 2.3rd Department of Surgery, “AHEPA” University HospitalAristotle University of ThessalonikiThessalonikiGreece

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