MUSCULOSKELETAL SURGERY

, Volume 95, Issue 2, pp 69–80 | Cite as

Electrospun scaffolds for bone tissue engineering

  • Alberto Di Martino
  • Liliana Liverani
  • Alberto Rainer
  • Giuseppe Salvatore
  • Marcella Trombetta
  • Vincenzo Denaro
Review

Abstract

Tissue engineering aims to regenerate native tissues and will represent the alternative choice of standard surgery for different kind of tissue damages. The fundamental basis of tissue engineering is the appropriate selection of scaffolds and their morphological, mechanical, chemical, and biomimetic properties, closely related to cell lines that will be seeded therein. The aim of this review is to summarize and report the innovative scientific contributions published in the field of orthopedic tissue engineering, in particular about bone tissue engineering. We have focused our attention on the electrospinning technique, as a scaffold fabrication method. Electrospun materials are being evaluated as scaffolds for bone tissue engineering, and the results of all these studies clearly indicate that they represent suitable potential substrates for cell-based technologies.

Keywords

Bone tissue engineering Electrospinning Nanofibers Scaffold Stem cells 

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Alberto Di Martino
    • 1
  • Liliana Liverani
    • 2
  • Alberto Rainer
    • 2
  • Giuseppe Salvatore
    • 1
  • Marcella Trombetta
    • 2
  • Vincenzo Denaro
    • 1
  1. 1.Department of Orthopaedics and Trauma SurgeryUniversity Campus Bio-Medico of RomeRomeItaly
  2. 2.CIR - Tissue Engineering LaboratoryUniversity Campus Bio-Medico of RomeRomeItaly

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