Skip to main content
SpringerLink
Log in

Detection of BCR/PDGRFα Fusion Using Dual Colour Dual Fusion BCR/ABL1 Probe: An Illustrative Report

  • Correspondence
  • Published:
Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Beau MML et al (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127(20):2391–2405

    Article  CAS  PubMed  Google Scholar 

  2. Reiter A, Gotlib J (2017) Myeloid neoplasms with eosinophilia. Blood 129(6):704–714

    Article  CAS  PubMed  Google Scholar 

  3. Baxter EJ, Hochhaus A, Bolufer P, Reiter A, Fernandez JM, Senent L et al (2002) The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA. Hum Mol Genet 11(12):1391–1397

    Article  CAS  PubMed  Google Scholar 

  4. Trempat P, Villalva C, Laurent G, Armstrong F, Delsol G, Dastugue N et al (2003) Chronic myeloproliferative disorders with rearrangement of the platelet-derived growth factor alpha receptor: a new clinical target for STI571/Glivec. Oncogene 22(36):5702–5706

    Article  CAS  PubMed  Google Scholar 

  5. Safley AM, Sebastian S, Collins TS, Tirado CA, Stenzel TT, Gong JZ et al (2004) Molecular and cytogenetic characterization of a novel translocation t(4;22) involving the breakpoint cluster region and platelet-derived growth factor receptor-alpha genes in a patient with atypical chronic myeloid leukemia. Genes Chromosomes Cancer 40(1):44–50

    Article  CAS  PubMed  Google Scholar 

  6. Erben P, Gosenca D, Muller MC, Relnhard J, Score J, Valle F et al (2010) Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis. Haematologica 95(5):738–744

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Wang HY, Thorson JA, Broome HE, Rashidi HH, Curtin PC, Dell’Aquila ML (2011) t(4;22)(q12;q11.2) involving presumptive platelet-derived growth factor receptor A and break cluster region in a patient with mixed phenotype acute leukemia. Hum Pathol 42:2029–2036

    Article  CAS  PubMed  Google Scholar 

  8. Yigit N, Wu WW, Subramaniyam S, Mathew S, Geyer JT (2015) BCR–PDGFRA fusion in a T lymphoblastic leukemia/lymphoma. Cancer Genet 208(7):404–407

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cytogenetics, Tata Medical Center, Kolkata, India

    Manish Kumar Singh & Arun Sasikumaran Nair Remani

  2. Department of Clinical Haematology, Tata Medical Center, Kolkata, India

    Saurabh Jayant Bhave

  3. Department of Lab Haematology and Molecular Genetics, Tata Medical Center, Kolkata, India

    Deppak Kumar Mishra & Neeraj Arora

  4. Department of Cytogenetics and Lab Haematology, Tata Medical Center, Kolkata, India

    Mayur Parihar

Authors
  1. Manish Kumar Singh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Arun Sasikumaran Nair Remani
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Saurabh Jayant Bhave
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Deppak Kumar Mishra
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Neeraj Arora
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mayur Parihar
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mayur Parihar.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Singh, M.K., Sasikumaran Nair Remani, A., Bhave, S.J. et al. Detection of BCR/PDGRFα Fusion Using Dual Colour Dual Fusion BCR/ABL1 Probe: An Illustrative Report. Indian J Hematol Blood Transfus 35, 570–574 (2019). https://doi.org/10.1007/s12288-019-01095-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12288-019-01095-9

Search

Navigation