Advertisement

Acute Myelopathy as the First Manifestation in a Hitherto Undiagnosed Case of Chronic Myeloid Leukemia

  • Ashish Aggarwal
  • Kokkula PraneethEmail author
  • Anurodh Kumar
  • Nishant Jindal
  • Pankaj Malhotra
Correspondence
  • 3 Downloads

Dear Editor,

Inspite of being a myeloproliferative disorder, abnormal bleeding is one of the rare manifestations of Chronic myeloid leukemia (CML) especially during chronic phase. This abnormal bleeding can have varied symptomatology depending upon the site of bleed. Sometime it may so happen in a clinical scenario that presence of underlying CML may come to attention by the symptoms of hematoma. We report a case of acute myelopathy because of spontaneous spinal epidural hematoma (SSEH) which turned out to be because of underlying undiagnosed CML.

A 48-year-old male presented to emergency with complaints of neck pain for 15 days and weakness of upper and lower limbs with bowel and bladder incontinence for last 3 days. There was no preceding history of trauma or fever. Examination revealed flaccid quadriparesis (Frankel scale C). Systemic examination revealed splenomegaly. MRI of cervical spine was suggestive of right posterolateral epidural lesion from C3 to D2 level. This lesion was...

Notes

References

  1. 1.
    Banerjee R, Stanley J, Palumbo M (2004) Spinal epidural hematoma induced by leukemia. Orthopedics 27(8):864–866Google Scholar
  2. 2.
    Chauhan S, Suri V, Varma S, Malhotra P, Varma N, Kaur A et al (2007) Granulocytic sarcoma: an unusual cause of compressive myelopathy. Am J Hematol 82(7):687–688CrossRefGoogle Scholar
  3. 3.
    Giugno A, Basile L, Maugeri R, Iacopino DG (2014) Emergency surgery in a patient with large spontaneous spinal epidural hematoma determining excellent neurological recovery: review of the literature. Spinal Cord 52(Suppl 3):S22–S24CrossRefGoogle Scholar
  4. 4.
    Nojiri H, Kim S, Tsuji T, Uta S (2009) Spontaneous spinal epidural hematoma as the initial presentation of leukemia. Eur Spine J 18(Suppl 2):220–223CrossRefGoogle Scholar
  5. 5.
    Schafer AI (1984) Bleeding and thrombosis in the myeloproliferative disorders. Blood 64(1):1–12Google Scholar

Copyright information

© Indian Society of Hematology and Blood Transfusion 2019

Authors and Affiliations

  • Ashish Aggarwal
    • 1
  • Kokkula Praneeth
    • 1
    Email author
  • Anurodh Kumar
    • 1
  • Nishant Jindal
    • 2
  • Pankaj Malhotra
    • 2
  1. 1.Department of NeurosurgeryPGIMERChandigarhIndia
  2. 2.Department of Internal MedicinePGIMERChandigarhIndia

Personalised recommendations