Chromosome 12 Rearrangement in an Adolescent with Primary Myelofibrosis
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Primary myelofibrosis (PMF) is a Philadelphia negative myeloproliferative neoplasm with bone marrow megakaryocytic and granulocytic proliferation along with fibrosis and extramedullary hematopoiesis. There is a sequential evolution in PMF from a prefibrotic to a fibrotic stage .
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Conflict of interest
Authors declares that he/she has no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from individual participant included in the study.
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