Passenger Lymphocyte Syndrome Following Minor ABO Mismatch Liver Transplantation
Non-ABO identical liver transplantation (LT) is in growing trend in India due to limited availability of organ donors and the growing number of patients awaiting orthotopic liver transplantation. Recipients of minor ABO mismatched organ transplantation may experience delayed hemolysis mediated by donor lymphocytes contained in the graft. Donor lymphocytes produce iso-agglutinins capable of destroying the recipient’s red cells, resulting in varying degree of hemolysis known as passenger lymphocyte syndrome (PLS) . PLS is not an uncommon cause of anemia in non-ABO identical LT but often goes undiagnosed and not yet reported in India in ABO mismatch LT.
Compliance with Ethical Standards
All procedures were in accordance to ethical standards. Informed consent was taken from the patient before blood transfusions.
Conflict of interest
The authors declare that they have no conflict of interest.