Incidental Discovery of Anti-IH in a Patient Planned for Caesarean Section and it’s Repercussions



Anti-IH Compound antibody Pan-agglutination Pregnant woman 


Compliance with Ethical Standards

Conflict of interest

There is no conflict of interest to declare.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


  1. 1.
    Ibanez C, Habibi A, Mekontso-Dessap A, Chadebech P, Chami B, Bierling P et al (2016) Anti-HI can cause a severe delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease patients. Transfusion 56:1828–1833CrossRefPubMedGoogle Scholar
  2. 2.
    Boonyasampant M, Weitz IC, Kay B, Boonchalermvichian C, Liebman HA, Shulman IA (2015) Life-threatening delayed hyperhemolytic transfusion reaction in a patient with sickle cell disease: effective treatment with eculizumab followed by rituximab. Transfusion 55:2398–2403CrossRefPubMedGoogle Scholar
  3. 3.
    Irani MS, Richards C (2011) Hemolytic transfusion reaction due to anti-IH. Transfusion 51:2676–2678CrossRefPubMedGoogle Scholar
  4. 4.
    Darabi K, Makar RS (2008) Acute hemolysis of transfused A2 red cells by an auto-HI antibody. Transfusion 48:964–968CrossRefPubMedGoogle Scholar
  5. 5.
    Campbell SA, Shirey RS, King KE, Ness PM (2000) An acute hemolytic transfusion reaction due to anti-IH in a patient with sickle cell disease. Transfusion 40:828–831CrossRefPubMedGoogle Scholar

Copyright information

© Indian Society of Hematology and Blood Transfusion 2017

Authors and Affiliations

  1. 1.Dalian Blood CenterDalianChina

Personalised recommendations