Indian Journal of Hematology and Blood Transfusion

, Volume 30, Issue 3, pp 195–196 | Cite as

Pleural Effusion as an Unusual Initial Presentation of Acute Myeloid Leukemia

  • Mukul Agarwal
  • Abhishek HL Purohit
  • Manoranjan Mahapatra
  • Rajeev Kumar
  • Pravas Mishra
  • Tulika Seth
  • Renu Saxena
Short Communication
  • 76 Downloads

Abstract

Pleural effusions in acute myeloid leukemia (AML) can have wide differential diagnosis, however AML presenting as pleural effusion with leukemic infiltration is rarely documented. A 22 year old male presented with pleural effusion for 3 months and subsequently diagnosed as AML M2, which prompted us for this communication.

Keywords

Malignant pleural effusion Acute myeloid leukemia Hematologic malignancy 

References

  1. 1.
    Johnston W (1985) The malignant pleural effusion. A review of cytopathologic diagnoses of 584 specimens from 472 consecutive patients. Cancer 56:905–909PubMedCrossRefGoogle Scholar
  2. 2.
    Light R (2001) Primary effusions related to metastatic malignancies. In: Light R (ed) Pleural diseases, 4th edn. Lea & Febiger, Philadelphia, pp 108–134Google Scholar
  3. 3.
    Awashi A, Gupta N, Srinivasan R et al (2007) Cytopathological spectrum of unusual malignant pleural effusions at a tertiary care centre in North India. Cytopathology 18:28–32CrossRefGoogle Scholar
  4. 4.
    Farray D, Al-Masri H, Hattersley E, Smith SE (2005) Megakaryoblastic leukemia with involvement of the pleural fluid. Am J Hematol 79:238–239PubMedCrossRefGoogle Scholar
  5. 5.
    Mufti G, Oscier D, Hamblin TJ, Nightingale A, Darlow S (1984) Serous effusions in monocytic leukemias. Br J Hematol 58:547–552CrossRefGoogle Scholar
  6. 6.
    Cakir E, Demirag F, Aydin M, Erdogan Y (2011) A review of uncommon cytopathologic diagnoses of pleural effusions from a chest diseases center in Turkey. Cytojournal 8:13PubMedCentralPubMedCrossRefGoogle Scholar
  7. 7.
    Fatih T, Selim Y, Mesut A, Demirel YN, Yuksel P (2007) An unusual cause of unilateral pleural effusion in the setting of aortic stenosis: acute myeloid leukemia. Intern Med 46:325–327PubMedCrossRefGoogle Scholar
  8. 8.
    Green AR, Campbell IA, Poynton C, Bentley DP (1989) Acute myeloid leukaemia presenting with pleural effusions. Clin Lab Haematol 11:399–401PubMedCrossRefGoogle Scholar
  9. 9.
    Disel U, Yavuz S, Paydas S, Sahin B, Zeren H (2003) Extramedullary relapse in the pleura in acute promyelocytic leukemia. Leuk Lymphoma 44:189–191PubMedCrossRefGoogle Scholar
  10. 10.
    Ou MC, Hwang WL, Teng CL (2011) Leukaemic pleural effusion in acute myeloid leukaemia. Br J Haematol 154:669CrossRefGoogle Scholar

Copyright information

© Indian Society of Haematology & Transfusion Medicine 2014

Authors and Affiliations

  • Mukul Agarwal
    • 1
  • Abhishek HL Purohit
    • 1
  • Manoranjan Mahapatra
    • 1
  • Rajeev Kumar
    • 1
  • Pravas Mishra
    • 1
  • Tulika Seth
    • 1
  • Renu Saxena
    • 1
  1. 1.Department of HematologyAll India Institute of Medical SciencesNew DelhiIndia

Personalised recommendations