Indian Journal of Hematology and Blood Transfusion

, Volume 29, Issue 3, pp 173–177

Successful Management of Chronic Refractory Immune Thrombocytopenia with Laparoscopic Splenectomy in a Patient with Acute Promyelocytic Leukemia

  • Ahmet Emre Eskazan
  • Ayse Salihoglu
  • Emine Gulturk
  • Seniz Ongoren Aydin
  • Nukhet Tuzuner
  • Yildiz Aydin
Case Report


Acute promyelocytic leukemia (APL) is a particular type of acute myeloid leukemia with characteristic biological and clinical features, the frequent association at diagnosis of a severe hemorrhagic diathesis. Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Here we present a patient with the diagnosis of APL who achieved and maintained a remission with an induction consisting of idarubicin and ATRA, and then developed corticosteroid refractory ITP which is successfully treated with laparoscopic splenectomy.


Immune thrombocytopenia ITP Splenectomy Acute promyelocytic leukemia APL 


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Copyright information

© Indian Society of Haematology & Transfusion Medicine 2012

Authors and Affiliations

  • Ahmet Emre Eskazan
    • 1
  • Ayse Salihoglu
    • 2
  • Emine Gulturk
    • 2
  • Seniz Ongoren Aydin
    • 2
  • Nukhet Tuzuner
    • 3
  • Yildiz Aydin
    • 2
  1. 1.Department of HematologyDiyarbakir Training and Research HospitalDiyarbakirTurkey
  2. 2.Division of Hematology, Department of Internal Medicine, Cerrahpasa Faculty of MedicineIstanbul UniversityIstanbulTurkey
  3. 3.Department of Pathology, Cerrahpasa Faculty of MedicineIstanbul UniversityIstanbulTurkey

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