Sickle cell disease and malaria

Review

Abstract

Malaria is most common infectious disease spread by female Anopheles mosquitoes especially in tropical and subtropical areas of the world. It is reported by WHO as a 4th leading cause of death in children across the developing countries. Unfortunately no vaccine is currently available. Sickle cell trait (HbAS) patients provide some resistance for malaria over normal persons (HbAA) or their homozygous state (HbSS) due to various reasons.

Keywords

Falciparum malaria Sickle cell trait Sickle cell disease 

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Copyright information

© Indian Society of Haematology & Transfusion Medicine 2007

Authors and Affiliations

  1. 1.Department of Pathology, J. N. Medical CollegeAligarh Muslim UniversityAligarhIndia

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