A dynamical systems approach for the submaximal prediction of maximum heart rate and maximal oxygen uptake
Abstract
This study examines the viability of utilizing a dynamical system model and heuristic parameter estimation algorithm to make predictions for maximum heart rate (\(\mathrm {HR_{max}}\)) and maximal oxygen uptake (\(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\)) using data collected from a submaximal testing protocol. \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) is widely considered to be the best single measurement of overall fitness in humans. When a \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) assessment is not available, \(\mathrm {HR_{max}}\) is often used to prescribe exercise intensities for training and rehabilitation. In the absence of maximal cardiopulmonary exercise testing (CPET), \(\mathrm {HR_{max}}\) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) are typically estimated using traditional submaximal prediction methods with well-known limitations and inaccuracies. For this study, 12 regularly exercising healthy young adult males performed a bout of maximal CPET on a cycle ergometer to determine their true \(\mathrm {HR_{max}}\) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\). Participants also performed a submaximal bout of exercise at varied intensities. A dynamical system model and heuristic parameter estimation algorithm were applied to the submaximal data to estimate the participants’ \(\mathrm {HR_{max}}\) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\). The submaximal predictions were evaluated by computing the coefficient of determination \({R^2}\) and the standard error of the estimate (SEE) through comparisons with the true maximal values for \(\mathrm {HR_{max}}\) (\({R^2 = 0.96}\), SEE = 2.4 bpm) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) (\({R^2 = 0.93}\), SEE = 2.1 mL kg\(^{-1}\) min\(^{-1}\)). The results from this study suggest that a dynamical system model and heuristic parameter estimation algorithm can provide accurate predictions for \(\mathrm {HR_{max}}\) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) using data collected from a submaximal testing protocol.
Keywords
Dynamical systems Heuristic algorithms Maximal oxygen uptake Maximum heart rate Nonlinear dynamics Parameter estimation Submaximal predictionsNotes
Compliance with ethical standards
Conflict of interest
The authors have filed a U.S. provisional patent application (No. 62/271,411) and an international patent application (PCT/US2016/068814) related to the systems and methods for predicting \(\mathrm {HR_{max}}\) and \(\dot{\mathrm {V}}{\mathrm {O_{2max}}}\) discussed in this paper.
Ethical standard
All aspects of this study were approved by the institutional review board, and informed written consent was obtained from each participant.
References
- 1.Akalan C, Robergs RA, Kravitz L (2008) Prediction of \({\dot{\rm V}{\rm O_{2max}}}\) from an individualized submaximal cycle ergometer protocol. J Exerc Physiol Online 11(2):1–17Google Scholar
- 2.de Araújo CGS, Duarte CV (2015) Maximal heart rate in young adults: a fixed 188 bpm outperforms values predicted by a classical age-based equation. Int J Cardiol 184:609–610. doi: 10.1016/j.ijcard.2015.02.043 CrossRefGoogle Scholar
- 3.Arena R, Myers J, Kaminsky LA (2016) Revisiting age-predicted maximal heart rate: can it be used as a valid measure of effort? Am Heart J 173:49–56. doi: 10.1016/j.ahj.2015.12.006 CrossRefGoogle Scholar
- 4.Asteroth A, Hagg A (2015) How to successfully apply genetic algorithms in practice: representation and parametrization. In: Proceedings of the 2015 international symposium on innovations in intelligent systems and applications. doi: 10.1109/INISTA.2015.7276778
- 5.Barstow TJ, Mole PA (1991) Linear and nonlinear characteristics of oxygen uptake kinetics during heavy exercise. J Appl Physiol 71(6):2099–2106CrossRefGoogle Scholar
- 6.Brooks GA, Fahey TD, Baldwin K (2005) Exercise physiology: human bioenergetics and its applications. McGraw-Hill, BostonGoogle Scholar
- 7.DiMenna FJ, Jones AM (2009) Linear versus nonlinear \({\dot{\rm V}{\rm O_{2}}}\) responses to exercise: reshaping traditional beliefs. J Exerc Sci Fit 7(2):67–84. doi: 10.1016/S1728-869X(09)60009-5
- 8.Fitchett MA (1985) Predictability of \({\dot{\rm V}{\rm O_{2max}}}\) from submaximal cycle ergometer and bench stepping tests. Br J Sports Med 19(2):85–88. doi: 10.1136/bjsm.19.2.85
- 9.Füller M, Sundaram AM, Ludwig M, Asteroth A, Prassler E (2015) Modeling and predicting the human heart rate during running exercise. In: Helfert M, Holzinger A, Ziefle M, Fred A, O'Donoghue J, Röcker C (eds) Information and communication technologies for ageing well and e-health. Springer, Cham, pp 106–125Google Scholar
- 10.Greiwe JS, Kaminsky LA, Whaley MH, Dwyer GB (1995) Evaluation of the ACSM submaximal ergometer test for estimating \({\dot{\rm V}{\rm O_{2max}}}\). Med Sci Sports Exerc 27(9):1315–1320Google Scholar
- 11.Howley ET, Bassett DR Jr, Welch HG (1995) Criteria for maximal oxygen uptake: review and commentary. Med Sci Sports Exerc 27(9):1292–1301. doi: 10.1249/00005768-199509000-00009 CrossRefGoogle Scholar
- 12.Jamnick NA, By S, Pettitt CD, Pettitt RW (2016) Comparison of the YMCA and a custom submaximal exercise test for determining \({\dot{\rm V}{\rm O_{2max}}}\). Med Sci Sports Exerc 48(2):254–259. doi: 10.1249/MSS.0000000000000763
- 13.Johnson AT (2007) Biomechanics and exercise physiology: quantitative modeling. CRC Press, Boca RatoCrossRefGoogle Scholar
- 14.Jones AM, Grassi B, Christensen PM, Krustrup P, Bangsbo J, Poole DC (2011) Slow component of \({\dot{\rm V}{\rm O_{2}}}\) kinetics: mechanistic bases and practical applications. Med Sci Sports Exerc 43(11):2046–2062. doi: 10.1249/MSS.0b013e31821fcfc1
- 15.Le A, Jaitner T, Tobias F, Litz L (2008) A dynamic heart rate prediction model for training optimization in cycling (P83). In: The engineering of sport 7. Springer, Paris, pp 425–433. doi: 10.1007/978-2-287-99054-0_50
- 16.Lefever J, Berckmans D, Aerts JM (2014) Time-variant modelling of heart rate responses to exercise intensity during road cycling. Eur J Sport Sci 14(1S):406–412. doi: 10.1080/17461391.2012.708791 CrossRefGoogle Scholar
- 17.Mann BP, Khasawneh FA, Fales R (2011) Using information to generate derivative coordinates from noisy time series. Commun Nonlinear Sci Numer Simul 16(8):2999–3004. doi: 10.1016/j.cnsns.2010.11.011 CrossRefMATHGoogle Scholar
- 18.Mazzoleni MJ, Battaglini CL, Martin KJ, Coffman EM, Mann BP (2016) Modeling and predicting heart rate dynamics across a broad range of transient exercise intensities during cycling. Sports Eng 19(2):117–127. doi: 10.1007/s12283-015-0193-3 CrossRefGoogle Scholar
- 19.Nes BM, Janszky I, Wisløff U, Støylen A, Karlsen T (2013) Age-predicted maximal heart rate in healthy subjects: the HUNT fitness study. Scand J Med Sci Sports 23(6):697–704. doi: 10.1111/j.1600-0838.2012.01445.x CrossRefGoogle Scholar
- 20.Özyener F, Rossiter HB, Ward SA, Whipp BJ (2001) Influence of exercise intensity on the on- and off-transient kinetics of pulmonary oxygen uptake in humans. J Physiol 533(3):891–902. doi: 10.1111/j.1469-7793.2001.t01-1-00891.x CrossRefGoogle Scholar
- 21.Perrey S, Burnley M, Millet GP, Jones AM, Poole DC, Gimenez P, Hughson RL, Capelli C, Zoladz JA, Perrey S, Grassi B, Bangsbo J, Rossiter HB, Linnarsson D, Quistorff B, Billat VL, Borrani F, Copp SW, Hirai DM, Busso T, Pogliaghi S, Korzeniewski B, Gill H, Petot H, Sarre G, Hamard L (2009) Comments on point: counterpoint: the kinetics of oxygen uptake during muscular exercise do/do not manifest time-delayed phases. J Appl Physiol 107(5):1669–1675CrossRefGoogle Scholar
- 22.Rao SS (2009) Engineering optimization: theory and practice. Wiley, HobokenCrossRefGoogle Scholar
- 23.Robergs RA, Burnett AF (2003) Methods used to process data from indirect calorimetry and their application to \({\dot{\rm V}{\rm O_{2max}}}\). J Exerc Physiol Online 6(2):44–57Google Scholar
- 24.Robergs RA, Dwyer D, Astorino T (2010) Recommendations for improved data processing from expired gas analysis indirect calorimetry. Sports Med 40(2):95–111. doi: 10.2165/11319670-000000000-00000 CrossRefGoogle Scholar
- 25.Robergs RA, Landwehr R (2002) The surprising history of the HRmax = 220-age equation. J Exerc Physiol Online 5(2):1–10Google Scholar
- 26.Sarzynski MA, Rankinen T, Earnest CP, Leon AS, Rao DC, Skinner JS, Bouchard C (2013) Measured maximal heart rates compared to commonly used age-based prediction equations in the heritage family study. Am J Hum Biol 25(5):695–701. doi: 10.1002/ajhb.22431 CrossRefGoogle Scholar
- 27.Smirmaul BPC, Bertucci DR, Teixeira IP (2013) Is the \({\dot{\rm V}{\rm O_{2max}}}\) that we measure really maximal? Front Physiol 4(203):1–4. doi: 10.3389/fphys.2013.00203
- 28.Stirling JR, Zakynthinaki MS (2009) Last word on point: counterpoint: the kinetics of oxygen uptake during muscular exercise do/do not manifest time-delayed phases. J Appl Physiol 107(5):1676CrossRefGoogle Scholar
- 29.Stirling JR, Zakynthinaki MS, Billat V (2008) Modeling and analysis of the effect of training on \({\dot{\rm V}{\rm O_{2}}}\) kinetics and anaerobic capacity. Bull Math Biol 70(5):1348–1370. doi: 10.1007/s11538-008-9302-9
- 30.Stirling JR, Zakynthinaki MS, Refoyo I, Sampedro J (2008) A model of heart rate kinetics in response to exercise. J Nonlinear Math Phys 15(3S):426–436. doi: 10.2991/jnmp.2008.15.s3.41 MathSciNetCrossRefGoogle Scholar
- 31.Stirling JR, Zakynthinaki MS, Saltin B (2005) A model of oxygen uptake kinetics in response to exercise: including a means of calculating oxygen demand/deficit/debt. Bull Math Biol 67(5):989–1015. doi: 10.1016/j.bulm.2004.12.005 MathSciNetCrossRefMATHGoogle Scholar
- 32.Storer TW, Davis JA, Caiozzo VJ (1990) Accurate prediction of \({\dot{\rm V}{\rm O_{2max}}}\) in cycle ergometry. Med Sci Sports Exerc 22(5):704–712Google Scholar
- 33.Tanaka H, Monahan KD, Seals DR (2001) Age-predicted maximal heart rate revisited. J Am Coll Cardiol 37(1):153–156. doi: 10.1016/S0735-1097(00)01054-8 CrossRefGoogle Scholar
- 34.Wagner PD (1996) Determinants of maximal oxygen transport and utilization. Ann Rev Physiol 58:21–50. doi: 10.1146/annurev.ph.58.030196.000321 CrossRefGoogle Scholar
- 35.Whipp BJ, Stirling JR, Zakynthinaki MS (2009) Point: counterpoint: the kinetics of oxygen uptake during muscular exercise do/do not manifest time-delayed phases. J Appl Physiol 107(5):1663–1668CrossRefGoogle Scholar
- 36.Whipp BJ, Wasserman K (1972) Oxygen uptake kinetics for various intensities of constant-load work. J Appl Physiol 33(3):351–356CrossRefGoogle Scholar
- 37.Wilcox SL, Broxterman RM, Barstow TJ (2016) Constructing quasi-linear \({\dot{\rm V}{\rm O_{2max}}}\) responses from nonlinear parameters. J Appl Physiol 120(2):121–129. doi: 10.1152/japplphysiol.00507.2015
- 38.Zakynthinaki MS (2015) Modelling heart rate kinetics. PLoS One 10(4):e0118263. doi: 10.1371/journal.pone.0118263 CrossRefGoogle Scholar
- 39.Zakynthinaki MS (2016) Simulating heart rate kinetics during incremental and interval training. Biomed Hum Kinet 8(1):144–152. doi: 10.1515/bhk-2016-0021 Google Scholar