Breast Cancer

, Volume 27, Issue 1, pp 100–110 | Cite as

Developing a checksheet for breast cancer patients receiving endocrine therapy-examining reliability and validity

  • Yukiko IiokaEmail author
  • Takako Iwata
  • Hideko Yamauchi
Original Article



The aim was to develop a checksheet that comprehends the daily lives of breast cancer patients receiving endocrine therapy, and examine its reliability and validity.


An anonymous, cross-sectional questionnaire was given to breast cancer patients under the age of 50 who had been receiving endocrine therapy for less than 1 year at outpatient clinical oncology offices in three facilities. Reliability was examined using Cronbach’s alpha and test–retest reliability. Content validity, face validity, concurrent validity, convergent validity/discriminant validity, and factor analysis were used to examine validity. The study was carried out with approval from the research ethics committee.


The checksheet was composed of three sections: subjective symptoms, discomforts in daily life while undergoing treatment, and coping with stress. Content validity was assessed as being mostly appropriate, and items identified as needing revision were corrected. Factor analysis led to four factors and 22 items for subjective symptoms, five factors and 18 items for daily life while undergoing treatment, and six factors and 24 items for coping with stress. Results indicated a high degree of correlation for concurrent validity, a moderate degree of correlation for convergent validity, and a low degree of correlation for discriminant validity.


This study verified that the checksheet in its initial development as a scale has high reliability and validity.


Breast cancer Endocrine therapy Checksheet Scale development 



Quality of life


Functional Assessment Of Cancer Therapy-Breast


Profile of Mood States Brief Form


Visual Analog Scale


Analysis Moment Structure


Standard Deviation


Goodness-of-Fit Index


Adjusted Goodness-of-Fit Index



We are extremely grateful to all the breast cancer patients who cooperated in this study, which was implemented through a subsidy for “Development of a Self-treatment System: focusing on breast cancer patients undergoing hormone treatment” (No. 2265940) from the Ministry of Education, Culture, Sports, Science and Technology Grant-in-Aid for Challenging Exploratory Research.

Compliance with ethical standard

Ethical considerations

Participants were given both written and oral explanations regarding cooperating in this study. They were informed that the merits or demerits of cooperating in this study would have absolutely no impact on treatment and that returning the anonymous questionnaire was voluntary. Its return by post to the principal researcher was regarded as consent to participate. The collected questionnaires were assigned new numbers, processed, and carefully kept. This study was conducted with approval from the research ethics committee of the institution to which the principal researcher belongs and the cooperating facilities (Showa University No. 1164, St. Luke’s International Hospital 11-R119, St. Luke’s International University 11-(streamlined review)-003).

Conflict of interest

Yukiko Iioka declares that she has no conflict of interest. Takako Iwata declares that she has no conflict of interest. Hideko Yamauchi declares that she has no conflict of interest.


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Copyright information

© The Japanese Breast Cancer Society 2019

Authors and Affiliations

  1. 1.Graduate Course of Health and Social ServicesSaitama Prefectural UniversitySaitamaJapan
  2. 2.Department of Breast CenterSt Luke’s International HospitalTokyoJapan

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