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Breast Cancer

, Volume 23, Issue 5, pp 706–711 | Cite as

Digital mammography versus digital breast tomosynthesis for detection of breast cancer in the intraoperative specimen during breast-conserving surgery

  • Misugi UranoEmail author
  • Norio Shiraki
  • Tatsuya Kawai
  • Taeko Goto
  • Yumi Endo
  • Nobuyasu Yoshimoto
  • Tatsuya Toyama
  • Yuta Shibamoto
Original Article

Abstract

Purpose

To compare the diagnostic ability of specimen radiography using digital mammography (DM) and digital breast tomosynthesis (DBT) for detecting breast cancer and evaluating its extension in the intraoperative specimen.

Methods

Sixty-five specimens from 65 women (median 62 years; range 34–86) obtained during breast-conserving surgery were prospectively investigated. Specimens underwent DM (25–40 kVp, 12–322 mA s) and DBT (25–34 kVp, 13–137 mA) in two orthogonal planes, anteroposterior (AP) and latero-lateral (LL). Images were interpreted by a radiologist to detect invasive lesions and their extensive intraductal components (EIC) or ductal carcinomas in situ (DCIS); afterwards, they were compared with histopathological findings.

Results

In AP views, 96 % of the invasive lesions were detected by both the methods. Of the EICs, 55 and 65 % were detected by DM and DBT, respectively (P = 0.61). Of the DICSs, 31 and 38 % were detected by DM and DBT, respectively (P > 0.99). In LL views, 71 and 13 % of the invasive lesions were detected by DBT and DM, respectively (P < 0.0001). Of the EICs, 42 and 10 % were detected by DBT and DM, respectively (P = 0.0078). Of the 13 DCISs, 42 and 8 % were detected by DBT and DM, respectively (P = 0.32). The whole lesion and contour could be delineated in 45 % by DBT and in 6.2 % by DM (P < 0.0001).

Conclusions

DBT could detect breast cancer more accurately than DM in LL views, indicating its potential to more precisely diagnose vertical invasion.

Keywords

Breast cancer Breast-conserving surgery Tomosynthesis Specimen mammography Margin assessment 

Notes

Acknowledgments

The authors wish to thank radiology technologists at Nagoya City University Hospital for taking DM and DBT. No funding exists for this research.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© The Japanese Breast Cancer Society 2015

Authors and Affiliations

  1. 1.Department of RadiologyNagoya City University Graduate School of Medical SciencesNagoyaJapan
  2. 2.Department of RadiologyNagoya City West Medical CenterNagoyaJapan
  3. 3.Department of Oncology, Immunology and SurgeryNagoya City University Graduate School of Medical SciencesNagoyaJapan

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