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Chromoblastomycosis in Solid Organ Transplant Recipients

  • Raaka Kumbhakar
  • Benjamin A. MikoEmail author
Fungal Infections of Skin and Subcutaneous Tissue (A Bonifaz and M Pereira, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Fungal Infections of Skin and Subcutaneous Tissue

Abstract

Purpose of review

There is growing recognition of melanized fungi as uncommon but important causes of infection among solid organ transplant recipients. Chromoblastomycosis and phaeohyphomycosis exist at opposing ends of the spectrum of disease caused by these fungi. We aim to systematically review the reports of chromoblastomycosis among transplant recipients to assess for trends in epidemiology and clinical outcomes.

Recent Findings

We identified 19 reported cases of histologically confirmed chromoblastomycosis among solid organ transplant recipients published between 1985 and 2018. Despite these patients’ impaired immunity, chromoblastomycosis remained localized to the skin and subcutaneous tissue in the majority of patients. Clinical outcomes were generally good with medical, surgical, or combined management.

Summary

Although chromoblastomycosis has a low incidence in this population, it is important to consider as a cause of chronic, non-healing skin infections. Further research is needed to better elucidate the impact of transplantation on the natural course of this condition.

Keywords

Chromoblastomycosis Melanized fungi Dematiaceous fungi Transplantation 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. 1.Department of Medicine, College of Physicians and SurgeonsColumbia UniversityNew YorkUSA
  2. 2.Division of Infectious Diseases, College of Physicians and SurgeonsColumbia UniversityNew YorkUSA

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