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The Southern Endemic Zone of Paracoccidioidomycosis: Epidemiological Approach in Northeast Argentina

  • Gustavo Giusiano
  • Florencia Rojas
  • Javier Mussin
  • Liliana Alegre
  • María de los Ángeles Sosa
Clinical Mycology Lab Issues (S Córdoba, Section Editor)
  • 4 Downloads
Part of the following topical collections:
  1. Topical Collection on Clinical Mycology Lab Issues

Abstract

Purpose of Review

Paracoccidioidomycosis (PCM) is one of the most prevalent systemic endemic mycosis in Latin America caused by species of an environmental fungus of the genus Paracoccidioides. In Argentina, the endemic area with the highest incidence is located in the Northeast. This review presents the current aspects of PCM epidemiology influenced by global and particular climatic anomalies.

Recent Findings

An increase of cases with particularly features, in the diagnosis and clinical manifestations, delaying the diagnosis was observed. Two genotypes of Paracoccidioides are circulating and, probably, are related to a considerable percentage of non-reactive serological tests obtained in proven cases of PCM.

Summary

The traditional view of the PCM epidemiology in the southern endemic zone area must be reconsidered. A higher level of premonition is now required in Northeast Argentina and, may be, in bordering countries. The particular characteristics both in the clinic and in the diagnosis currently observed suggest a new trend in PCM.

Keywords

Paracoccidioidomycosis Epidemiology Climatic influence Argentina 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Gustavo Giusiano
    • 1
  • Florencia Rojas
    • 1
  • Javier Mussin
    • 1
  • Liliana Alegre
    • 1
  • María de los Ángeles Sosa
    • 1
    • 2
  1. 1.Departamento de Micología, Instituto de Medicina Regional, CONICETUniversidad Nacional del NordesteResistenciaArgentina
  2. 2.Laboratorio Central de Salud PúblicaCorrientesArgentina

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