Current Fungal Infection Reports

, Volume 9, Issue 4, pp 220–228 | Cite as

Hyperendemia of Sporotrichosis in the Brazilian Southeast: Learning From Clinics and Therapeutics

  • Rosane Orofino-Costa
  • Priscila Marques de Macedo
  • Andréa Reis Bernardes-Engemann
Fungal Infections of Skin and Subcutaneous Tissue (A Bonifaz, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Fungal Infections of Skin and Subcutaneous Tissue


The molecular identification of the Sporothrix schenckii complex has not only changed epidemiology data but has also shown atypical clinical features leading to new therapeutic challenges. S. brasiliensis is the main etiological agent of the biggest feline zoonotic transmission to be reported in southeast Brazil since the late 1990s. Its phenotype has also changed as a result of the production of melanin in primary cultures from patient-affected sites; it is thus thought to be a more virulent species. Elderly, children, pregnant women, and immunosuppressed patients, particularly AIDS patients, are special groups that are at risk. More aggressive diseases have been observed in apparently immunocompetent patients. This article is intended to review the main aspects of clinical and therapeutic approaches that have been learned from the epidemics.


Sporotrichosis Sporothrix brasiliensis Sporothrix schenckii Treatment Potassium iodide Itraconazole Terbinafine Cryosurgery Thermotherapy 


Compliance with Ethics Guidelines

Conflict of Interest

Rosane Orofino-Costa, Priscila Marques de Macedo, and Andréa Reis Bernardes-Engemann declare that they have no conflict of interest

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Rosane Orofino-Costa
    • 1
    • 3
  • Priscila Marques de Macedo
    • 2
  • Andréa Reis Bernardes-Engemann
    • 1
  1. 1.Hospital Universitário Pedro ErnestoUniversidade do Estado do Rio de Janeiro (UERJ)Rio de JaneiroBrazil
  2. 2.Instituto Nacional de Infectologia Evandro Chagas (INI)Rio de JaneiroBrazil
  3. 3.Rio de JaneiroBrazil

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