Nano Research

, Volume 3, Issue 10, pp 738–747 | Cite as

Movable Au microplates as fluorescence enhancing substrates for live cells

  • Boya Radha
  • Mohammed Arif
  • Ranjan Datta
  • Tapas K. Kundu
  • Giridhar U. KulkarniEmail author
Open Access
Research Article


Hexagonal and triangular Au microplates extending over an area of ?12,000 ?m2 with thickness in the range 30–1000 nm have been synthesized using a single step thermolysis of (AuCl4)?-tetraoctylammonium bromide complex in air. The microplates are self-supporting and can be easily manipulated using a sharp pin, a property which enables them to serve as substrates for living cells. The microplate surface is non-toxic to living cells and can enhance the fluorescence signal from fluorophores residing within the cell by an order of magnitude. In addition, the microplates are smooth and single-crystalline, and ideal as microscopy substrates and molecular electrodes. The growth of the microplates in the initial stages is interesting in that they seem to grow perpendicular to the substrate, as evidenced by in situ microscopy. Open image in new window


Au microplates synthesis cell substrate metal enhanced fluorescence manipulation 

Supplementary material

12274_2010_40_MOESM1_ESM.pdf (1.6 mb)
Supplementary material, approximately 1.64 MB.


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Copyright information

© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Boya Radha
    • 1
  • Mohammed Arif
    • 2
  • Ranjan Datta
    • 3
  • Tapas K. Kundu
    • 2
  • Giridhar U. Kulkarni
    • 1
    Email author
  1. 1.Chemistry and Physics of Materials Unit and DST Unit on NanoscienceJawaharlal Nehru Centre for Advanced Scientific ResearchBangaloreIndia
  2. 2.Molecular Biology and Genetics UnitJawaharlal Nehru Centre for Advanced Scientific ResearchBangaloreIndia
  3. 3.International Centre for Materials ScienceJawaharlal Nehru Centre for Advanced Scientific ResearchBangaloreIndia

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