Size-dependent joule heating of gold nanoparticles using capacitively coupled radiofrequency fields
- 2.3k Downloads
Capacitively coupled shortwave radiofrequency fields (13.56 MHz) resistively heat low concentrations (∼1 ppm) of gold nanoparticles with a thermal power dissipation of ∼380 kW/g of gold. Smaller diameter gold nanoparticles (< 50 nm) heat at nearly twice the rate of larger diameter gold nanoparticles (≥50 nm), which is attributed to the higher resistivity of smaller gold nanostructures. A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.
KeywordsResistivity radiofrequency gold nanoparticles cancer thermal
- Gannon, C. J.; Cherukuri, P.; Yakobson, B. I.; Cognet, L.; Kanzius, J. S.; Kittrell, C.; Weisman, R. B.; Pasquali, M.; Schmidt, H. K.; Smalley, R. E.; Curley, S. A. Carbon nanotube-enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field. Cancer 2007, 110, 2654–2665.CrossRefPubMedGoogle Scholar
- Kanzius, J. S. U.S. Patent Pub. Nos. US 2006/0190063 A1, US2005/02511233 A1, US2005/0251234 A1, and World Intellectual Property Organization WO 2007/027614Google Scholar
- Kittel, C. Introduction to Solid State Physics; J. Wiley & Sons: New York, NY, 2005.Google Scholar
- Metaxas, A. C. Foundations of Electroheat: A Unified Approach; J. Wiley & Sons: New York, NY, 1996.Google Scholar