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Archives of Pharmacal Research

, Volume 36, Issue 10, pp 1185–1188 | Cite as

Gemigliptin, a novel dipeptidyl peptidase 4 inhibitor: first new anti-diabetic drug in the history of Korean pharmaceutical industry

  • Sung-Ho Kim
  • Sung-Hack Lee
  • Hyeon-Joo YimEmail author
Report on Investigational Drugs

Abstract

Gemigliptin, a potent, selective and long-acting DPP 4 inhibitor was developed by LG Life Sciences and approved for use in patients with type 2 diabetes mellitus by the Korean Food and Drug Administration in June 2012 under the trade name Zemiglo®. Clinical pharmacokinetic and pharmacodynamic data suggest the efficacy and once daily dosing of gemigliptin. In clinical phase III studies, gemigliptin was efficacious as either monotherapy or combination therapy (add-on to metformin) and well tolerated in patients with type 2 diabetes. Further development of combination therapy is on-going.

Keywords

Metformin Sitagliptin Vildagliptin Saxagliptin Linagliptin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This study was partially supported by a grant from the Ministry of Knowledge Economy (Bio-Star, 10024075).

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Copyright information

© The Pharmaceutical Society of Korea 2013

Authors and Affiliations

  1. 1.LG Life Science R&D ParkDaejeonKorea

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