Archives of Pharmacal Research

, Volume 35, Issue 3, pp 461–468 | Cite as

Tetrahydroanthraquinone and xanthone derivatives from the marine-derived fungus Trichoderma aureoviride PSU-F95

  • Nanthaphong Khamthong
  • Vatcharin Rukachaisirikul
  • Kwanruthai Tadpetch
  • Morakot Kaewpet
  • Souwalak Phongpaichit
  • Sita Preedanon
  • Jariya Sakayaroj
Research Articles Drug Design and Discovery
First Online:
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Accepted:

Abstract

Trichodermaquinone (1) and trichodermaxanthone (2) were isolated from the marine-derived fungus Trichoderma aureoviride PSU-F95 together with eleven known compounds. The structures were interpreted by spectroscopic methods. Known coniothranthraquinone 1 and emodin displayed strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC values of 8 and 4 μg/mL, respectively.

Key words

Trichoderma aureoviride Marine-derived fungus Tetrahydroanthraquinone Xanthone Antibacterial activity 
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Copyright information

© The Pharmaceutical Society of Korea and Springer Netherlands 2012

Authors and Affiliations

  • Nanthaphong Khamthong
    • 1
  • Vatcharin Rukachaisirikul
    • 1
    • 4
  • Kwanruthai Tadpetch
    • 1
  • Morakot Kaewpet
    • 1
  • Souwalak Phongpaichit
    • 2
  • Sita Preedanon
    • 3
  • Jariya Sakayaroj
    • 3
  1. 1.Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of SciencePrince of Songkla UniversityHat Yai, SongkhlaThailand
  2. 2.Natural Products Research Center and Department of Microbiology, Faculty of SciencePrince of Songkla UniversityHat Yai, SongkhlaThailand
  3. 3.National Center for Genetic Engineering and Biotechnology (BIOTEC)Thailand Science ParkKlong Luang, PathumthaniThailand
  4. 4.Department of Chemistry, Faculty of SciencePrince of Songkla UniversitySongkhlaThailand

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