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A new stilbene glucoside gallate from the roots of Polygonum multiflorum

  • Hyun Ki Kim
  • Yeon Hee Choi
  • Jae Seok Choi
  • Sang Un Choi
  • Young Sup Kim
  • Kang Ro Lee
  • Young-Kyoon Kim
  • Shi Yong RyuEmail author
Research Article Drug Discovery

Abstract

A new stilbenoid (1) was isolated from the root extract of Polygonum multiflorum together with eight known constituents (2∼9). The chemical structure of 1 was established as the 6″-O-monogalloyl ester of (E)-2,3,4′,5-β-tetrahydroxystilbene-2-β-D-glucopyranoside based on physicochemical and spectroscopic analyses, particularly by NMR spectroscopic data, i.e., COSY, HMQC and HMBC. Compound 1 weakly inhibited acetylcholinesterase in vitro.

Key words

Polygonum multiflorum Polygonaceae (E)-2,3,4′,5-tetrahydroxystilbene-2-β-D-glucoside Stilbene glucoside gallate 

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Copyright information

© The Pharmaceutical Society of Korea 2008

Authors and Affiliations

  • Hyun Ki Kim
    • 3
  • Yeon Hee Choi
    • 3
  • Jae Seok Choi
    • 3
  • Sang Un Choi
    • 3
  • Young Sup Kim
    • 3
  • Kang Ro Lee
    • 1
    • 3
  • Young-Kyoon Kim
    • 2
    • 3
  • Shi Yong Ryu
    • 3
    Email author
  1. 1.College of PharmacySungkyunkwan UniversitySuwonKorea
  2. 2.College of Forest ScienceKookmin UniversitySeoulKorea
  3. 3.Korea Research Institute of Chemical TechnologyDaejeonKorea

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