New polyunsaturated fatty acid amides isolated from the seeds of Zanthoxylum piperitum
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Five linear fatty acid amides (1–5) of the sandshool class, including two new compounds, were isolated from Zanthoxylum piperitum seeds. Based on combined spectral analyses, the structures of new compounds 4 and 5 were determined to be 2′,3′-dihydroxy-α-sanshool and 2′,3′-dihydroxy-β-sanshool, respectively. These compounds exhibited weak cytotoxicity in the A-549 (human lung cancer) cell line.
Key wordsZanthoxylum piperitum Fatty acid amides Sanshools Dihydroxy-α-sanshool Dihydroxy-β-sanshool Cytotoxicity
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