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BIOspektrum

, Volume 25, Issue 6, pp 680–682 | Cite as

Chirale Epoxidierung von Aryl-Alkyl-Ethern aus Lignin

  • Daniel Eggerichs
  • Anna C. Lienkamp
  • Thomas Heine
  • Carolin Mügge
  • Dirk TischlerEmail author
Biotechnologie Biokatalyse

Abstract

Processing of lignin provides access to mono-aromatic compounds with a styrene-like structure. The vinyl sidechain can be attacked by monooxygenases, such as styrene or indole monooxygenases, to yield enantiopure epoxides. The obtained epoxides can be converted into valuable products, either enzyme- or non-enzyme driven. This provides access to drug-like molecules and technically relevant synthesis precursors. Herein, we report the setup of a simple screening strategy for useful epoxidases.

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Copyright information

© Springer-Verlag 2019

Authors and Affiliations

  • Daniel Eggerichs
    • 1
  • Anna C. Lienkamp
    • 1
  • Thomas Heine
    • 2
  • Carolin Mügge
    • 1
  • Dirk Tischler
    • 1
    Email author
  1. 1.NG Mikrobielle BiotechnologieRuhr-Universität BochumBochumDeutschland
  2. 2.AG UmweltmikrobiologieTU Bergakademie FreibergFreibergDeutschland

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