, Volume 21, Issue 4, pp 406–410 | Cite as

Patientenspezifische iPS-Zellen und deren Anwendung in der Herzforschung

  • Katrin Streckfuß-Bömeke
  • Lukas Cyganek
Wissenschaft · Special: Zellbiologie iPS-Zellen


A major research focus in the field of cardiovascular medicine is the prospect of using stem cells for cardiac regeneration. With the advent of induced pluripotent stem cell (iPSC) technology, major efforts are also in process to use iPSCs for modelling heart disease, screening for new drugs, and the development of treatment strategies on a patient-specific level. Here we describe the generation of iPSCs, their efficient differentiation into functional cardiomyocytes, and the power of the iPSC technology for modelling dilative cardiomyopathy on a patient-specific level.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Klinik für Kardiologie und PneumologieUniversitätsmedizin GöttingenGöttingenDeutschland

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