Abstract
There is a fundamental gap in our understanding of how horizontal gene transfer contributes to the enormous range of genetic variations that are observed among bacteria. Our model organism is Vibrio cholerae, the causative agent of cholera. V. cholerae enters a natural competence state for the uptake of DNA in response to environmental signals. Our objective is to better understand the regulatory circuits that drive competence in this organism and the mechanistic aspects of the DNA transfer and uptake process.
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Melanie Blokesch 1995–2000 Biologiestudium an der LMU München. 2000–2004 Promotion unter der Leitung von Prof. Dr. A. Böck am Department Biology I der LMU München. 2005–2009 Postdoc an der Stanford University, CA, USA. Seit 2009 Tenure-track Assistant Professor an der Eidgenössischen Technischen Hochschule Lausanne (EPFL), Schweiz.
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Blokesch, M. Leben und sterben lassen – horizontaler Gentransfer in Vibrio cholerae . Biospektrum 21, 273–276 (2015). https://doi.org/10.1007/s12268-015-0572-0
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DOI: https://doi.org/10.1007/s12268-015-0572-0