BIOspektrum

, Volume 18, Issue 4, pp 449–451 | Cite as

Expressionsoptimierung in Mikroorganismen

Forschungsplattform ExpressO
  • Achim Heck
  • Denis Tielker
  • Joachim F. Ernst
  • Roland Freudl
  • Michael Bott
  • Marco Oldiges
  • Wolfgang Wiechert
  • Jörg Pietruszka
  • Susanne Wilhelm
  • Frank Rosenau
  • Thomas Drepper
  • Karl-Erich Jaeger
Biotechnologie

Abstract

The genome era lead to the identification of a tremendous number of genes encoding potentially scientific and biotechnological relevant proteins. Moreover, the number of these proteins is still exponentially growing. Nevertheless, the corresponding genes have to be expressed to produce functional proteins thereby constituting a huge scientific, industrial and economic challenge. This challenge was taken by the CLIB2021 Technology Platform Protein Expression and Optimization (ExpressO).

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Achim Heck
    • 1
    • 9
    • 2
  • Denis Tielker
    • 3
    • 8
  • Joachim F. Ernst
    • 3
  • Roland Freudl
    • 4
  • Michael Bott
    • 4
  • Marco Oldiges
    • 4
  • Wolfgang Wiechert
    • 5
  • Jörg Pietruszka
    • 6
  • Susanne Wilhelm
    • 1
    • 2
  • Frank Rosenau
    • 7
  • Thomas Drepper
    • 1
    • 2
  • Karl-Erich Jaeger
    • 1
    • 9
  1. 1.Institut für Molekulare EnzymtechnologieUniversität DüsseldorfDüsseldorfGermany
  2. 2.Forschungszentrum JülichJülichGermany
  3. 3.Institut für Molekulare MykologieUniversität DüsseldorfDüsseldorfGermany
  4. 4.Institut für Bio- und Geowissenschaften 1: BiotechnologieSystemische MikrobiologieForschungszentrum JülichGermany
  5. 5.Institut für Bio- und Geowissenschaften 1: Biotechnologie, SystembiologieForschungszentrum JülichGermany
  6. 6.Institut für Bioorganische ChemieUniversität DüsseldorfForschungszentrum JülichGermany
  7. 7.Institut für Mikrobiologie und BiotechnologieUniversität UlmUlmGermany
  8. 8.Qiagen GMBHHildenGermany
  9. 9.Institut für Molekulare Enzymtechnologie Heinrich-Heine-Universität Düsseldorf Forschungszentrum JülichJülichGermany

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