Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy
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A recent working group meeting focused on contemporary cardiac issues in Duchenne muscular dystrophy (DMD) was hosted by the National Heart, Lung, and Blood Institute in collaboration with the Parent Project Muscular Dystrophy. An outcome of this meeting was to provide freely available detailed protocols for preclinical animal studies. The goal of these protocols is to improve the quality and reproducibility of cardiac preclinical studies aimed at developing new therapeutics for the prevention and treatment of DMD cardiomyopathy.
KeywordsDuchenne Cardiology Cardiomyopathy Standard operating procedures (SOPs) Preclinical
The authors thank the National Heart, Lung, and Blood Institute and the Parent Project Muscular Dystrophy.
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Conflict of Interest
D.D. is a member of the scientific advisory board for Solid GT, a subsidiary of Solid Biosciences. The Duan lab received research support from Solid Biosciences in 2014 and 2015. The other authors report no conflicts.